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Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death. [electronic resource] by
- Argueta, Christian
- Kashyap, Trinayan
- Klebanov, Boris
- Unger, Thaddeus J
- Guo, Cathy
- Harrington, Susie
- Baloglu, Erkan
- Lee, Margaret
- Senapedis, William
- Shacham, Sharon
- Landesman, Yosef
Publication details: Oncotarget May 2018
In:
Oncotarget vol. 9
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Selinexor reduces the expression of DNA damage repair proteins and sensitizes cancer cells to DNA damaging agents. [electronic resource] by
- Kashyap, Trinayan
- Argueta, Christian
- Unger, Thaddeus
- Klebanov, Boris
- Debler, Sophia
- Senapedis, William
- Crochiere, Marsha L
- Lee, Margaret S
- Kauffman, Michael
- Shacham, Sharon
- Landesman, Yosef
Publication details: Oncotarget Jul 2018
In:
Oncotarget vol. 9
Availability: No items available.
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9.
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Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic Cancer. [electronic resource] by
- Kazim, Sabiha
- Malafa, Mokenge P
- Coppola, Domenico
- Husain, Kazim
- Zibadi, Sherma
- Kashyap, Trinayan
- Crochiere, Marsha
- Landesman, Yosef
- Rashal, Tami
- Sullivan, Daniel M
- Mahipal, Amit
Producer: 20160510
In:
Molecular cancer therapeutics vol. 14
Availability: No items available.
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XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma. [electronic resource] by
- Turner, Joel G
- Kashyap, Trinayan
- Dawson, Jana L
- Gomez, Juan
- Bauer, Alexis A
- Grant, Steven
- Dai, Yun
- Shain, Kenneth H
- Meads, Mark
- Landesman, Yosef
- Sullivan, Daniel M
Producer: 20180223
In:
Oncotarget vol. 7
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XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus. [electronic resource] by
- Ranganathan, Parvathi
- Kashyap, Trinayan
- Yu, Xueyan
- Meng, Xiaomei
- Lai, Tzung-Huei
- McNeil, Betina
- Bhatnagar, Bhavana
- Shacham, Sharon
- Kauffman, Michael
- Dorrance, Adrienne M
- Blum, William
- Sampath, Deepa
- Landesman, Yosef
- Garzon, Ramiro
Producer: 20180112
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 22
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Novel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells. [electronic resource] by
- Yang, Jennifer
- Bill, Matthew A
- Young, Gregory S
- La Perle, Krista
- Landesman, Yosef
- Shacham, Sharon
- Kauffman, Michael
- Senapedis, William
- Kashyap, Trinayan
- Saint-Martin, Jean-Richard
- Kendra, Kari
- Lesinski, Gregory B
Producer: 20150421
In:
PloS one vol. 9
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The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors. [electronic resource] by
- Farren, Matthew R
- Hennessey, Rebecca C
- Shakya, Reena
- Elnaggar, Omar
- Young, Gregory
- Kendra, Kari
- Landesman, Yosef
- Elloul, Sivan
- Crochiere, Marsha
- Klebanov, Boris
- Kashyap, Trinayan
- Burd, Christin E
- Lesinski, Gregory B
Producer: 20170629
In:
Molecular cancer therapeutics vol. 16
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Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death. [electronic resource] by
- Kashyap, Trinayan
- Argueta, Christian
- Aboukameel, Amro
- Unger, Thaddeus John
- Klebanov, Boris
- Mohammad, Ramzi M
- Muqbil, Irfana
- Azmi, Asfar S
- Drolen, Claire
- Senapedis, William
- Lee, Margaret
- Kauffman, Michael
- Shacham, Sharon
- Landesman, Yosef
Producer: 20180223
In:
Oncotarget vol. 7
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Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression. [electronic resource] by
- Aboukameel, Amro
- Muqbil, Irfana
- Baloglu, Erkan
- Senapedis, William
- Landesman, Yosef
- Argueta, Christian
- Kauffman, Michael
- Chang, Hua
- Kashyap, Trinayan
- Shacham, Sharon
- Neggers, Jasper E
- Daelemans, Dirk
- Heath, Elisabeth I
- Azmi, Asfar S
Publication details: Oncotarget Oct 2018
In:
Oncotarget vol. 9
Availability: No items available.
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Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas. [electronic resource] by
- Saenz-Ponce, Natalia
- Pillay, Rachael
- de Long, Lilia Merida
- Kashyap, Trinayan
- Argueta, Christian
- Landesman, Yosef
- Hazar-Rethinam, Mehlika
- Boros, Samuel
- Panizza, Benedict
- Jacquemyn, Maarten
- Daelemans, Dirk
- Gannon, Orla M
- Saunders, Nicholas A
Producer: 20191004
In:
Science translational medicine vol. 10
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Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis. [electronic resource] by
- Machlus, Kellie R
- Wu, Stephen K
- Vijey, Prakrith
- Soussou, Thomas S
- Liu, Zhi-Jian
- Shacham, Eran
- Unger, T J
- Kashyap, Trinayan
- Klebanov, Boris
- Sola-Visner, Martha
- Crochiere, Marsha
- Italiano, Joseph E
- Landesman, Yosef
Producer: 20170925
In:
Blood vol. 130
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Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma. [electronic resource] by
- DeSisto, John A
- Flannery, Patrick
- Lemma, Rakeb
- Pathak, Amrita
- Mestnik, Shelby
- Philips, Natalie
- Bales, Natalie J
- Kashyap, Trinayan
- Moroze, Erin
- Venkataraman, Sujatha
- Kung, Andrew L
- Carter, Bruce D
- Landesman, Yosef
- Vibhakar, Rajeev
- Green, Adam L
Producer: 20210111
In:
Molecular cancer therapeutics vol. 19
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Venetoclax response is enhanced by selective inhibitor of nuclear export compounds in hematologic malignancies. [electronic resource] by
- Fischer, Melissa A
- Friedlander, Sharon Y
- Arrate, Maria P
- Chang, Hua
- Gorska, Agnieszka E
- Fuller, Londa D
- Ramsey, Haley E
- Kashyap, Trinayan
- Argueta, Christian
- Debler, Sophie
- Byrne, Michael
- Villaume, Matthew T
- Shaver, Aaron C
- Senapedis, William
- Landesman, Yosef
- Baloglu, Erkan
- Shacham, Sharon
- Savona, Michael R
Producer: 20210514
In:
Blood advances vol. 4
Availability: No items available.
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A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia. [electronic resource] by
- Garzon, Ramiro
- Savona, Michael
- Baz, Rachid
- Andreeff, Michael
- Gabrail, Nashat
- Gutierrez, Martin
- Savoie, Lynn
- Mau-Sorensen, Paul Morten
- Wagner-Johnston, Nina
- Yee, Karen
- Unger, Thaddeus J
- Saint-Martin, Jean-Richard
- Carlson, Robert
- Rashal, Tami
- Kashyap, Trinayan
- Klebanov, Boris
- Shacham, Sharon
- Kauffman, Michael
- Stone, Richard
Producer: 20170817
In:
Blood vol. 129
Availability: No items available.
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