Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas. [electronic resource]
Producer: 20191004ISSN:- 1946-6242
- Active Transport, Cell Nucleus -- drug effects
- Animals
- Anthracyclines -- pharmacology
- Cell Line, Tumor
- Cell Nucleus -- drug effects
- Doxorubicin -- pharmacology
- Drug Resistance, Neoplasm -- drug effects
- E2F1 Transcription Factor -- metabolism
- E2F7 Transcription Factor -- metabolism
- Humans
- Karyopherins -- antagonists & inhibitors
- Mice, Inbred NOD
- Mice, SCID
- Molecular Targeted Therapy
- Phosphotransferases (Alcohol Group Acceptor) -- metabolism
- Receptors, Cytoplasmic and Nuclear -- antagonists & inhibitors
- Squamous Cell Carcinoma of Head and Neck -- metabolism
- Exportin 1 Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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