Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis. [electronic resource]
Producer: 20170925Description: 1132-1143 p. digitalISSN:- 1528-0020
- Animals
- Apoptosis -- drug effects
- Blood Platelets -- drug effects
- Bone Marrow -- drug effects
- Cell Count
- Cell Differentiation -- drug effects
- Dose-Response Relationship, Drug
- Fetus -- pathology
- Hydrazines -- adverse effects
- Liver -- embryology
- Megakaryocytes -- drug effects
- Mice, Knockout
- Platelet Activation -- drug effects
- Signal Transduction -- drug effects
- Stem Cells -- cytology
- Thrombocytopenia -- blood
- Thrombopoiesis -- drug effects
- Thrombopoietin -- metabolism
- Triazoles -- adverse effects
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Publication Type: Clinical Trial, Phase I; Journal Article
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