Results
|
|
1.
|
|
|
|
2.
|
|
|
|
3.
|
|
|
|
4.
|
|
|
|
5.
|
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors. [electronic resource] by
- Le Floch, Renaud
- Chiche, Johanna
- Marchiq, Ibtissam
- Naiken, Tanesha
- Naïken, Tanesha
- Ilc, Karine
- Ilk, Karine
- Murray, Clare M
- Critchlow, Susan E
- Roux, Danièle
- Simon, Marie-Pierre
- Pouysségur, Jacques
Producer: 20111213
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 108
Availability: No items available.
|
|
|
6.
|
Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters. [electronic resource] by
- Mehibel, Manal
- Ortiz-Martinez, Fernando
- Voelxen, Nadine
- Boyers, Amy
- Chadwick, Amy
- Telfer, Brian A
- Mueller-Klieser, Wolfgang
- West, Catharine M
- Critchlow, Susan E
- Williams, Kaye J
- Stratford, Ian J
Producer: 20191118
In:
Scientific reports vol. 8
Availability: No items available.
|
|
|
7.
|
Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. [electronic resource] by
- Polański, Radosław
- Hodgkinson, Cassandra L
- Fusi, Alberto
- Nonaka, Daisuke
- Priest, Lynsey
- Kelly, Paul
- Trapani, Francesca
- Bishop, Paul W
- White, Anne
- Critchlow, Susan E
- Smith, Paul D
- Blackhall, Fiona
- Dive, Caroline
- Morrow, Christopher J
Producer: 20141014
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 20
Availability: No items available.
|
|
|
8.
|
3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers. [electronic resource] by
- Jones, Dylan T
- Valli, Alessandro
- Haider, Syed
- Zhang, Qifeng
- Smethurst, Elizabeth A
- Schug, Zachary T
- Peck, Barrie
- Aboagye, Eric O
- Critchlow, Susan E
- Schulze, Almut
- Gottlieb, Eyal
- Wakelam, Michael J O
- Harris, Adrian L
Producer: 20191125
In:
Molecular cancer therapeutics vol. 18
Availability: No items available.
|
|
|
9.
|
Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis. [electronic resource] by
- Kettle, Jason G
- Ballard, Peter
- Bardelle, Catherine
- Cockerill, Mark
- Colclough, Nicola
- Critchlow, Susan E
- Debreczeni, Judit
- Fairley, Gary
- Fillery, Shaun
- Graham, Mark A
- Goodwin, Louise
- Guichard, Sylvie
- Hudson, Kevin
- Ward, Richard A
- Whittaker, David
Producer: 20150526
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
|
|
|
10.
|
Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging. [electronic resource] by
- Swales, John G
- Dexter, Alex
- Hamm, Gregory
- Nilsson, Anna
- Strittmatter, Nicole
- Michopoulos, Filippos
- Hardy, Christopher
- Morentin-Gutierrez, Pablo
- Mellor, Martine
- Andren, Per E
- Clench, Malcolm R
- Bunch, Josephine
- Critchlow, Susan E
- Goodwin, Richard J A
Producer: 20190417
In:
Analytical chemistry vol. 90
Availability: No items available.
|
|
|
11.
|
Combined Inhibition of PI3Kβ and mTOR Inhibits Growth of PTEN-null Tumors. [electronic resource] by
- Lynch, James T
- Polanska, Urszula M
- Hancox, Ursula
- Delpuech, Oona
- Maynard, Juliana
- Trigwell, Catherine
- Eberlein, Catherine
- Lenaghan, Carol
- Polanski, Radoslaw
- Avivar-Valderas, Alvaro
- Cumberbatch, Marie
- Klinowska, Teresa
- Critchlow, Susan E
- Cruzalegui, Francisco
- Barry, Simon T
Producer: 20190910
In:
Molecular cancer therapeutics vol. 17
Availability: No items available.
|
|
|
12.
|
Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity. [electronic resource] by
- Curtis, Nicola J
- Mooney, Lorraine
- Hopcroft, Lorna
- Michopoulos, Filippos
- Whalley, Nichola
- Zhong, Haihong
- Murray, Clare
- Logie, Armelle
- Revill, Mitchell
- Byth, Kate F
- Benjamin, Amanda D
- Firth, Mike A
- Green, Stephen
- Smith, Paul D
- Critchlow, Susan E
Publication details: Oncotarget Sep 2017
In:
Oncotarget vol. 8
Availability: No items available.
|
|
|
13.
|
Sulfonyl-morpholino-pyrimidines: SAR and development of a novel class of selective mTOR kinase inhibitor. [electronic resource] by
- Finlay, M Raymond V
- Buttar, David
- Critchlow, Susan E
- Dishington, Allan P
- Fillery, Shaun M
- Fisher, Eric
- Glossop, Steve C
- Graham, Mark A
- Johnson, Trevor
- Lamont, Gillian M
- Mutton, Simon
- Perkins, Paula
- Pike, Kurt G
- Slater, Anthony M
Producer: 20120925
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
|
|
|
14.
|
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma. [electronic resource] by
- Noble, Richard A
- Bell, Natalie
- Blair, Helen
- Sikka, Arti
- Thomas, Huw
- Phillips, Nicole
- Nakjang, Sirintra
- Miwa, Satomi
- Crossland, Rachel
- Rand, Vikki
- Televantou, Despina
- Long, Anna
- Keun, Hector C
- Bacon, Chris M
- Bomken, Simon
- Critchlow, Susan E
- Wedge, Stephen R
Producer: 20180326
In:
Haematologica vol. 102
Availability: No items available.
|
|
|
15.
|
Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer. [electronic resource] by
- Pommier, Aurélien J C
- Farren, Matthew
- Patel, Bhavika
- Wappett, Mark
- Michopoulos, Filippos
- Smith, Neil R
- Kendrew, Jane
- Frith, Jeremy
- Huby, Russell
- Eberlein, Catherine
- Campbell, Hayley
- Womack, Christopher
- Smith, Paul D
- Robertson, Jane
- Morgan, Shethah
- Critchlow, Susan E
- Barry, Simon T
Producer: 20161013
In:
Cell metabolism vol. 23
Availability: No items available.
|
|
|
16.
|
Inhibiting PI3Kβ with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors. [electronic resource] by
- Lynch, James T
- Polanska, Urszula M
- Delpuech, Oona
- Hancox, Urs
- Trinidad, Antonio G
- Michopoulos, Filippos
- Lenaghan, Carol
- McEwen, Robert
- Bradford, James
- Polanski, Radek
- Ellston, Rebecca
- Avivar-Valderas, Alvaro
- Pilling, James
- Staniszewska, Anna
- Cumberbatch, Marie
- Critchlow, Susan E
- Cruzalegui, Francisco
- Barry, Simon T
Producer: 20180801
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 23
Availability: No items available.
|
|
|
17.
|
A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors. [electronic resource] by
- St-Gallay, Stephen A
- Bennett, Neil
- Critchlow, Susan E
- Curtis, Nicola
- Davies, Gareth
- Debreczeni, Judit
- Evans, Nicola
- Hardern, Ian
- Holdgate, Geoff
- Jones, Neil P
- Leach, Lindsey
- Maman, Sarita
- McLoughlin, Sheila
- Preston, Marian
- Rigoreau, Laurent
- Thomas, Andrew
- Turnbull, Andrew P
- Walker, Graeme
- Walsh, Jarrod
- Ward, Richard A
- Wheatley, Ed
- Winter-Holt, Jon
Producer: 20190821
In:
SLAS discovery : advancing life sciences R & D vol. 23
Availability: No items available.
|
|
|
18.
|
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity. [electronic resource] by
- Chresta, Christine M
- Davies, Barry R
- Hickson, Ian
- Harding, Tom
- Cosulich, Sabina
- Critchlow, Susan E
- Vincent, John P
- Ellston, Rebecca
- Jones, Darren
- Sini, Patrizia
- James, Dominic
- Howard, Zoe
- Dudley, Phillippa
- Hughes, Gareth
- Smith, Lisa
- Maguire, Sharon
- Hummersone, Marc
- Malagu, Karine
- Menear, Keith
- Jenkins, Richard
- Jacobsen, Matt
- Smith, Graeme C M
- Guichard, Sylvie
- Pass, Martin
Producer: 20100126
In:
Cancer research vol. 70
Availability: No items available.
|
|
|
19.
|
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments. [electronic resource] by
- Peck, Barrie
- Schug, Zachary T
- Zhang, Qifeng
- Dankworth, Beatrice
- Jones, Dylan T
- Smethurst, Elizabeth
- Patel, Rachana
- Mason, Susan
- Jiang, Ming
- Saunders, Rebecca
- Howell, Michael
- Mitter, Richard
- Spencer-Dene, Bradley
- Stamp, Gordon
- McGarry, Lynn
- James, Daniel
- Shanks, Emma
- Aboagye, Eric O
- Critchlow, Susan E
- Leung, Hing Y
- Harris, Adrian L
- Wakelam, Michael J O
- Gottlieb, Eyal
- Schulze, Almut
Producer: 20160404
In:
Cancer & metabolism vol. 4
Availability: No items available.
|
|
|
20.
|
MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. [electronic resource] by
- Hong, Candice Sun
- Graham, Nicholas A
- Gu, Wen
- Espindola Camacho, Carolina
- Mah, Vei
- Maresh, Erin L
- Alavi, Mohammed
- Bagryanova, Lora
- Krotee, Pascal A L
- Gardner, Brian K
- Behbahan, Iman Saramipoor
- Horvath, Steve
- Chia, David
- Mellinghoff, Ingo K
- Hurvitz, Sara A
- Dubinett, Steven M
- Critchlow, Susan E
- Kurdistani, Siavash K
- Goodglick, Lee
- Braas, Daniel
- Graeber, Thomas G
- Christofk, Heather R
Producer: 20161108
In:
Cell reports vol. 14
Availability: No items available.
|