Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport. [electronic resource]
Producer: 20150811Description: 2805-16 p. digitalISSN:- 1538-8514
- Animals
- Biological Transport
- Cell Line, Tumor
- Cluster Analysis
- Disease Models, Animal
- Female
- Glycolysis -- drug effects
- Humans
- Lactates -- metabolism
- Metabolomics
- Monocarboxylic Acid Transporters -- antagonists & inhibitors
- Neoplasms -- drug therapy
- Oxidative Stress -- drug effects
- Pyrimidinones -- administration & dosage
- Radiation Tolerance -- drug effects
- Symporters -- antagonists & inhibitors
- Thiophenes -- administration & dosage
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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