Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis. [electronic resource]
Producer: 20150526Description: 2834-44 p. digitalISSN:- 1520-4804
- Animals
- COS Cells
- Cell Line, Tumor
- Chlorocebus aethiops
- Drug Discovery
- Drug Resistance
- Humans
- MAP Kinase Kinase Kinases -- antagonists & inhibitors
- Models, Molecular
- Protein Kinase Inhibitors -- chemistry
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering -- genetics
- Rats, Wistar
- Dyrk Kinases
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Publication Type: Journal Article
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