Inhibiting PI3Kβ with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors. [electronic resource]
Producer: 20180801Description: 7584-7595 p. digitalISSN:- 1557-3265
- Aniline Compounds -- administration & dosage
- Animals
- Cell Line, Tumor
- Chromones -- administration & dosage
- Class II Phosphatidylinositol 3-Kinases -- genetics
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Hydroxymethylglutaryl-CoA Synthase -- genetics
- Metabolic Networks and Pathways -- genetics
- Mice
- PTEN Phosphohydrolase -- genetics
- Triple Negative Breast Neoplasms -- drug therapy
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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