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Preferential inhibition of T helper 1, but not T helper 2, cytokines in vitro by L-826,141 [4-[2-(3,4-Bisdifluromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]3-methylpyridine-1-oxide], a potent and selective phosphodiesterase 4 inhibitor. [electronic resource] by Producer: 20050328
In:
The Journal of pharmacology and experimental therapeutics vol. 310
Availability: No items available.
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In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663). [electronic resource] by
- Chauret, N
- Yergey, J A
- Brideau, C
- Friesen, R W
- Mancini, J
- Riendeau, D
- Silva, J
- Styhler, A
- Trimble, L A
- Nicoll-Griffith, D A
Producer: 20010920
In:
Bioorganic & medicinal chemistry letters vol. 11
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L-454,560, a potent and selective PDE4 inhibitor with in vivo efficacy in animal models of asthma and cognition. [electronic resource] by
- Huang, Z
- Dias, R
- Jones, T
- Liu, S
- Styhler, A
- Claveau, D
- Otu, F
- Ng, K
- Laliberte, F
- Zhang, L
- Goetghebeur, P
- Abraham, W M
- Macdonald, D
- Dubé, D
- Gallant, M
- Lacombe, P
- Girard, Y
- Young, R N
- Turner, M J
- Nicholson, D W
- Mancini, J A
Producer: 20070702
In:
Biochemical pharmacology vol. 73
Availability: No items available.
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