Results
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41.
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42.
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2-(2-[3-(pyridin-3-yloxy)phenyl]-2H-tetrazol-5-yl) pyridine: a highly potent, orally active, metabotropic glutamate subtype 5 (mGlu5) receptor antagonist. [electronic resource] by
- Huang, Dehua
- Poon, Steve F
- Chapman, Deborah F
- Chung, Janice
- Cramer, Merryl
- Reger, Thomas S
- Roppe, Jeffrey R
- Tehrani, Lida
- Cosford, Nicholas D P
- Smith, Nicholas D
Producer: 20050322
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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43.
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Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2). [electronic resource] by
- Chaikuad, Apirat
- Koschade, Sebastian E
- Stolz, Alexandra
- Zivkovic, Katarina
- Pohl, Christian
- Shaid, Shabnam
- Ren, Huiyu
- Lambert, Lester J
- Cosford, Nicholas D P
- Brandts, Christian H
- Knapp, Stefan
Producer: 20191217
In:
The Biochemical journal vol. 476
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44.
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[3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: in vitro and in vivo characterization. [electronic resource] by
- Anderson, Jeffery J
- Rao, Sara P
- Rowe, Blake
- Giracello, Darlene R
- Holtz, Greg
- Chapman, Deborah F
- Tehrani, Lida
- Bradbury, Margaret J
- Cosford, Nicholas D P
- Varney, Mark A
Producer: 20021224
In:
The Journal of pharmacology and experimental therapeutics vol. 303
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45.
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Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity. [electronic resource] by
- Smith, Nicholas D
- Poon, Steve F
- Huang, Dehua
- Green, Mitchell
- King, Christopher
- Tehrani, Lida
- Roppe, Jeffrey R
- Chung, Janice
- Chapman, Deborah P
- Cramer, Merryl
- Cosford, Nicholas D P
Producer: 20050322
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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46.
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Identification of metabotropic glutamate receptor antagonists using an automated high-throughput screening system. [electronic resource] by
- Hodder, Peter
- Cassaday, Jason
- Peltier, Richard
- Berry, Kurtis
- Inglese, James
- Feuston, Bradley
- Culberson, Chris
- Bleicher, Leo
- Cosford, Nicholas D P
- Bayly, Chris
- Suto, Carla
- Varney, Mark
- Strulovici, Berta
Producer: 20030925
In:
Analytical biochemistry vol. 313
Availability: No items available.
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47.
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3-[Substituted]-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)benzonitriles: identification of highly potent and selective metabotropic glutamate subtype 5 receptor antagonists. [electronic resource] by
- Tehrani, Lida R
- Smith, Nicholas D
- Huang, Dehua
- Poon, Steve F
- Roppe, Jeffrey R
- Seiders, Thomas Jon
- Chapman, Deborah F
- Chung, Janice
- Cramer, Merryl
- Cosford, Nicholas D P
Producer: 20051223
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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48.
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A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors. [electronic resource] by
- Noberini, Roberta
- De, Surya K
- Zhang, Ziming
- Wu, Bainan
- Raveendra-Panickar, Dhanya
- Chen, Vida
- Vazquez, Jesus
- Qin, Haina
- Song, Jianxing
- Cosford, Nicholas D P
- Pellecchia, Maurizio
- Pasquale, Elena B
Producer: 20120105
In:
Chemical biology & drug design vol. 78
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49.
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Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production. [electronic resource] by
- Poksay, Karen S
- Sheffler, Douglas J
- Spilman, Patricia
- Campagna, Jesus
- Jagodzinska, Barbara
- Descamps, Olivier
- Gorostiza, Olivia
- Matalis, Alex
- Mullenix, Michael
- Bredesen, Dale E
- Cosford, Nicholas D P
- John, Varghese
Publication details: Frontiers in pharmacology 2017
In:
Frontiers in pharmacology vol. 8
Availability: No items available.
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50.
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3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity. [electronic resource] by
- Cosford, Nicholas D P
- Tehrani, Lida
- Roppe, Jeffrey
- Schweiger, Edwin
- Smith, Nicholas D
- Anderson, Jeffrey
- Bristow, Linda
- Brodkin, Jesse
- Jiang, Xiaohui
- McDonald, Ian
- Rao, Sara
- Washburn, Mark
- Varney, Mark A
Producer: 20030204
In:
Journal of medicinal chemistry vol. 46
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51.
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Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats. [electronic resource] by
- Dhanya, Raveendra-Panickar
- Sidique, Shyama
- Sheffler, Douglas J
- Nickols, Hilary Highfield
- Herath, Ananda
- Yang, Li
- Dahl, Russell
- Ardecky, Robert
- Semenova, Svetlana
- Markou, Athina
- Conn, P Jeffrey
- Cosford, Nicholas D P
Producer: 20111109
In:
Journal of medicinal chemistry vol. 54
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52.
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Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with anxiolytic activity. [electronic resource] by
- Roppe, Jeffrey
- Smith, Nicholas D
- Huang, Dehua
- Tehrani, Lida
- Wang, Bowei
- Anderson, Jeffrey
- Brodkin, Jesse
- Chung, Janice
- Jiang, Xiaohui
- King, Christopher
- Munoz, Benito
- Varney, Mark A
- Prasit, Petpiboon
- Cosford, Nicholas D P
Producer: 20041007
In:
Journal of medicinal chemistry vol. 47
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53.
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Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. [electronic resource] by
- Bravo, Yalda
- Teriete, Peter
- Dhanya, Raveendra-Panickar
- Dahl, Russell
- Lee, Pooi San
- Kiffer-Moreira, Tina
- Ganji, Santhi Reddy
- Sergienko, Eduard
- Smith, Layton H
- Farquharson, Colin
- Millán, José Luis
- Cosford, Nicholas D P
Producer: 20150330
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
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54.
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Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP. [electronic resource] by
- Ardecky, Robert J
- Welsh, Kate
- Finlay, Darren
- Lee, Pooi San
- González-López, Marcos
- Ganji, Santhi Reddy
- Ravanan, Palaniyandi
- Mace, Peter D
- Riedl, Stefan J
- Vuori, Kristiina
- Reed, John C
- Cosford, Nicholas D P
Producer: 20140121
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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55.
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Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1. [electronic resource] by
- Rong, Juan
- Pass, Ian
- Diaz, Paul W
- Ngo, Tram A
- Sauer, Michelle
- Magnuson, Gavin
- Zeng, Fu-Yue
- Hassig, Christian A
- Jackson, Michael R
- Cosford, Nicholas D P
- Matsuzawa, Shu-Ichi
- Reed, John C
Producer: 20161005
In:
Journal of biomolecular screening vol. 20
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56.
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Perturbation of the c-Myc-Max protein-protein interaction via synthetic α-helix mimetics. [electronic resource] by
- Jung, Kwan-Young
- Wang, Huabo
- Teriete, Peter
- Yap, Jeremy L
- Chen, Lijia
- Lanning, Maryanna E
- Hu, Angela
- Lambert, Lester J
- Holien, Toril
- Sundan, Anders
- Cosford, Nicholas D P
- Prochownik, Edward V
- Fletcher, Steven
Producer: 20150630
In:
Journal of medicinal chemistry vol. 58
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57.
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Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[ [electronic resource] by
- Zhang, Xiaofei
- Kumata, Katsushi
- Yamasaki, Tomoteru
- Cheng, Ran
- Hatori, Akiko
- Ma, Longle
- Zhang, Yiding
- Xie, Lin
- Wang, Lu
- Kang, Hye Jin
- Sheffler, Douglas J
- Cosford, Nicholas D P
- Zhang, Ming-Rong
- Liang, Steven H
Producer: 20180612
In:
ACS chemical neuroscience vol. 8
Availability: No items available.
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58.
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Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP. [electronic resource] by
- González-López, Marcos
- Welsh, Kate
- Finlay, Darren
- Ardecky, Robert J
- Ganji, Santhi Reddy
- Su, Ying
- Yuan, Hongbin
- Teriete, Peter
- Mace, Peter D
- Riedl, Stefan J
- Vuori, Kristiina
- Reed, John C
- Cosford, Nicholas D P
Producer: 20111025
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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59.
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Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. [electronic resource] by
- Wang, Huabo
- Teriete, Peter
- Hu, Angela
- Raveendra-Panickar, Dhanya
- Pendelton, Kelsey
- Lazo, John S
- Eiseman, Julie
- Holien, Toril
- Misund, Kristine
- Oliynyk, Ganna
- Arsenian-Henriksson, Marie
- Cosford, Nicholas D P
- Sundan, Anders
- Prochownik, Edward V
Producer: 20160812
In:
Oncotarget vol. 6
Availability: No items available.
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60.
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Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs. [electronic resource] by
- Finlay, Darren
- Vamos, Mitchell
- González-López, Marcos
- Ardecky, Robert J
- Ganji, Santhi Reddy
- Yuan, Hongbin
- Su, Ying
- Cooley, Trina R
- Hauser, Curt T
- Welsh, Kate
- Reed, John C
- Cosford, Nicholas D P
- Vuori, Kristiina
Producer: 20140929
In:
Molecular cancer therapeutics vol. 13
Availability: No items available.
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