Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. [electronic resource]
Producer: 20150330Description: 4308-11 p. digitalISSN:- 1464-3405
- Animals
- Benzamides -- chemical synthesis
- Benzothiazoles -- chemical synthesis
- Dose-Response Relationship, Drug
- Drug Design
- Enzyme Inhibitors -- chemical synthesis
- Hepatocytes -- drug effects
- High-Throughput Screening Assays
- Humans
- Hydrogen-Ion Concentration
- Mice
- Molecular Structure
- Phosphoric Monoester Hydrolases -- antagonists & inhibitors
- Small Molecule Libraries -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural
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