Results
|
|
41.
|
Identification of metabotropic glutamate receptor antagonists using an automated high-throughput screening system. [electronic resource] by
- Hodder, Peter
- Cassaday, Jason
- Peltier, Richard
- Berry, Kurtis
- Inglese, James
- Feuston, Bradley
- Culberson, Chris
- Bleicher, Leo
- Cosford, Nicholas D P
- Bayly, Chris
- Suto, Carla
- Varney, Mark
- Strulovici, Berta
Producer: 20030925
In:
Analytical biochemistry vol. 313
Availability: No items available.
|
|
|
42.
|
3-[Substituted]-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)benzonitriles: identification of highly potent and selective metabotropic glutamate subtype 5 receptor antagonists. [electronic resource] by
- Tehrani, Lida R
- Smith, Nicholas D
- Huang, Dehua
- Poon, Steve F
- Roppe, Jeffrey R
- Seiders, Thomas Jon
- Chapman, Deborah F
- Chung, Janice
- Cramer, Merryl
- Cosford, Nicholas D P
Producer: 20051223
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
|
|
|
43.
|
Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity. [electronic resource] by
- Smith, Nicholas D
- Poon, Steve F
- Huang, Dehua
- Green, Mitchell
- King, Christopher
- Tehrani, Lida
- Roppe, Jeffrey R
- Chung, Janice
- Chapman, Deborah P
- Cramer, Merryl
- Cosford, Nicholas D P
Producer: 20050322
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
|
|
|
44.
|
A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors. [electronic resource] by
- Noberini, Roberta
- De, Surya K
- Zhang, Ziming
- Wu, Bainan
- Raveendra-Panickar, Dhanya
- Chen, Vida
- Vazquez, Jesus
- Qin, Haina
- Song, Jianxing
- Cosford, Nicholas D P
- Pellecchia, Maurizio
- Pasquale, Elena B
Producer: 20120105
In:
Chemical biology & drug design vol. 78
Availability: No items available.
|
|
|
45.
|
Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production. [electronic resource] by
- Poksay, Karen S
- Sheffler, Douglas J
- Spilman, Patricia
- Campagna, Jesus
- Jagodzinska, Barbara
- Descamps, Olivier
- Gorostiza, Olivia
- Matalis, Alex
- Mullenix, Michael
- Bredesen, Dale E
- Cosford, Nicholas D P
- John, Varghese
Publication details: Frontiers in pharmacology 2017
In:
Frontiers in pharmacology vol. 8
Availability: No items available.
|
|
|
46.
|
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity. [electronic resource] by
- Cosford, Nicholas D P
- Tehrani, Lida
- Roppe, Jeffrey
- Schweiger, Edwin
- Smith, Nicholas D
- Anderson, Jeffrey
- Bristow, Linda
- Brodkin, Jesse
- Jiang, Xiaohui
- McDonald, Ian
- Rao, Sara
- Washburn, Mark
- Varney, Mark A
Producer: 20030204
In:
Journal of medicinal chemistry vol. 46
Availability: No items available.
|
|
|
47.
|
Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats. [electronic resource] by
- Dhanya, Raveendra-Panickar
- Sidique, Shyama
- Sheffler, Douglas J
- Nickols, Hilary Highfield
- Herath, Ananda
- Yang, Li
- Dahl, Russell
- Ardecky, Robert
- Semenova, Svetlana
- Markou, Athina
- Conn, P Jeffrey
- Cosford, Nicholas D P
Producer: 20111109
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
|
|
|
48.
|
Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with anxiolytic activity. [electronic resource] by
- Roppe, Jeffrey
- Smith, Nicholas D
- Huang, Dehua
- Tehrani, Lida
- Wang, Bowei
- Anderson, Jeffrey
- Brodkin, Jesse
- Chung, Janice
- Jiang, Xiaohui
- King, Christopher
- Munoz, Benito
- Varney, Mark A
- Prasit, Petpiboon
- Cosford, Nicholas D P
Producer: 20041007
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
|
|
|
49.
|
Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. [electronic resource] by
- Bravo, Yalda
- Teriete, Peter
- Dhanya, Raveendra-Panickar
- Dahl, Russell
- Lee, Pooi San
- Kiffer-Moreira, Tina
- Ganji, Santhi Reddy
- Sergienko, Eduard
- Smith, Layton H
- Farquharson, Colin
- Millán, José Luis
- Cosford, Nicholas D P
Producer: 20150330
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
|
|
|
50.
|
Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP. [electronic resource] by
- Ardecky, Robert J
- Welsh, Kate
- Finlay, Darren
- Lee, Pooi San
- González-López, Marcos
- Ganji, Santhi Reddy
- Ravanan, Palaniyandi
- Mace, Peter D
- Riedl, Stefan J
- Vuori, Kristiina
- Reed, John C
- Cosford, Nicholas D P
Producer: 20140121
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
|
|
|
51.
|
Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1. [electronic resource] by
- Rong, Juan
- Pass, Ian
- Diaz, Paul W
- Ngo, Tram A
- Sauer, Michelle
- Magnuson, Gavin
- Zeng, Fu-Yue
- Hassig, Christian A
- Jackson, Michael R
- Cosford, Nicholas D P
- Matsuzawa, Shu-Ichi
- Reed, John C
Producer: 20161005
In:
Journal of biomolecular screening vol. 20
Availability: No items available.
|
|
|
52.
|
Perturbation of the c-Myc-Max protein-protein interaction via synthetic α-helix mimetics. [electronic resource] by
- Jung, Kwan-Young
- Wang, Huabo
- Teriete, Peter
- Yap, Jeremy L
- Chen, Lijia
- Lanning, Maryanna E
- Hu, Angela
- Lambert, Lester J
- Holien, Toril
- Sundan, Anders
- Cosford, Nicholas D P
- Prochownik, Edward V
- Fletcher, Steven
Producer: 20150630
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
|
|
|
53.
|
Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[ [electronic resource] by
- Zhang, Xiaofei
- Kumata, Katsushi
- Yamasaki, Tomoteru
- Cheng, Ran
- Hatori, Akiko
- Ma, Longle
- Zhang, Yiding
- Xie, Lin
- Wang, Lu
- Kang, Hye Jin
- Sheffler, Douglas J
- Cosford, Nicholas D P
- Zhang, Ming-Rong
- Liang, Steven H
Producer: 20180612
In:
ACS chemical neuroscience vol. 8
Availability: No items available.
|
|
|
54.
|
5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity. [electronic resource] by
- Roppe, Jeffrey R
- Wang, Bowei
- Huang, Dehua
- Tehrani, Lida
- Kamenecka, Theodore
- Schweiger, Edwin J
- Anderson, Jeffery J
- Brodkin, Jesse
- Jiang, Xiaohui
- Cramer, Merryl
- Chung, Janice
- Reyes-Manalo, Grace
- Munoz, Benito
- Cosford, Nicholas D P
Producer: 20050412
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
|
|
|
55.
|
Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP. [electronic resource] by
- González-López, Marcos
- Welsh, Kate
- Finlay, Darren
- Ardecky, Robert J
- Ganji, Santhi Reddy
- Su, Ying
- Yuan, Hongbin
- Teriete, Peter
- Mace, Peter D
- Riedl, Stefan J
- Vuori, Kristiina
- Reed, John C
- Cosford, Nicholas D P
Producer: 20111025
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
|
|
|
56.
|
Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. [electronic resource] by
- Wang, Huabo
- Teriete, Peter
- Hu, Angela
- Raveendra-Panickar, Dhanya
- Pendelton, Kelsey
- Lazo, John S
- Eiseman, Julie
- Holien, Toril
- Misund, Kristine
- Oliynyk, Ganna
- Arsenian-Henriksson, Marie
- Cosford, Nicholas D P
- Sundan, Anders
- Prochownik, Edward V
Producer: 20160812
In:
Oncotarget vol. 6
Availability: No items available.
|
|
|
57.
|
Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs. [electronic resource] by
- Finlay, Darren
- Vamos, Mitchell
- González-López, Marcos
- Ardecky, Robert J
- Ganji, Santhi Reddy
- Yuan, Hongbin
- Su, Ying
- Cooley, Trina R
- Hauser, Curt T
- Welsh, Kate
- Reed, John C
- Cosford, Nicholas D P
- Vuori, Kristiina
Producer: 20140929
In:
Molecular cancer therapeutics vol. 13
Availability: No items available.
|
|
|
58.
|
A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors. [electronic resource] by
- Romero, Celeste
- Lambert, Lester J
- Sheffler, Douglas J
- De Backer, Laurent J S
- Raveendra-Panickar, Dhanya
- Celeridad, Maria
- Grotegut, Stefan
- Rodiles, Socorro
- Holleran, John
- Sergienko, Eduard
- Pasquale, Elena B
- Cosford, Nicholas D P
- Tautz, Lutz
Producer: 20201021
In:
The Journal of biological chemistry vol. 295
Availability: No items available.
|
|
|
59.
|
Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence. [electronic resource] by
- Sidique, Shyama
- Dhanya, Raveendra-Panickar
- Sheffler, Douglas J
- Nickols, Hilary Highfield
- Yang, Li
- Dahl, Russell
- Mangravita-Novo, Arianna
- Smith, Layton H
- D'Souza, Manoranjan S
- Semenova, Svetlana
- Conn, P Jeffrey
- Markou, Athina
- Cosford, Nicholas D P
Producer: 20130205
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
|
|
|
60.
|
Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis. [electronic resource] by
- Welsh, Kate
- Milutinovic, Snezana
- Ardecky, Robert J
- Gonzalez-Lopez, Marcos
- Ganji, Santhi Reddy
- Teriete, Peter
- Finlay, Darren
- Riedl, Stefan
- Matsuzawa, Shu-Ichi
- Pinilla, Clemencia
- Houghten, Richard
- Vuori, Kristiina
- Reed, John C
- Cosford, Nicholas D P
Producer: 20170802
In:
PloS one vol. 11
Availability: No items available.
|