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BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response. [electronic resource] by
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- Patel, Luv
- Flanagan, Annabelle
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- Sorger, Peter
- Letai, Anthony
Producer: 20131209
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Molecular cell vol. 51
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HSF1 phase transition mediates stress adaptation and cell fate decisions. [electronic resource] by
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- Li, Carmen G
- Lindquist, Susan L
- Sarosiek, Kristopher A
- Whitesell, Luke
- Sorger, Peter K
- Santagata, Sandro
Producer: 20200415
In:
Nature cell biology vol. 22
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Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma. [electronic resource] by
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- Cavallin, Lucas E
- Bhatt, Shruti
- Toomey, Ngoc L
- Natkunam, Yasodha
- Blasini, Wilfredo
- Gentles, Andrew J
- Ramos, Juan Carlos
- Mesri, Enrique A
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Producer: 20100901
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 107
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Short-term exposure to ambient particle gamma radioactivity is associated with increased risk for all-cause non-accidental and cardiovascular mortality. [electronic resource] by
- Huang, Shaodan
- Xiong, Jianyin
- Vieira, Carolina L Z
- Blomberg, Annelise J
- Gold, Diane R
- Coull, Brent A
- Sarosiek, Kristopher
- Schwartz, Joel D
- Wolfson, Jack M
- Li, Jing
- Koutrakis, Petros
Producer: 20200710
In:
The Science of the total environment vol. 721
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Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancers. [electronic resource] by
- Hata, Aaron N
- Yeo, Alan
- Faber, Anthony C
- Lifshits, Eugene
- Chen, Zhao
- Cheng, Katherine A
- Walton, Zandra
- Sarosiek, Kristopher A
- Letai, Anthony
- Heist, Rebecca S
- Mino-Kenudson, Mari
- Wong, Kwok-Kin
- Engelman, Jeffrey A
Producer: 20140828
In:
Cancer research vol. 74
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Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance. [electronic resource] by
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- Maillet, Laurent
- Le Pen, Janic
- Vuillier, Céline
- Trécesson, Sophie de Carné
- Fétiveau, Aurélie
- Sarosiek, Kristopher A
- Bock, Florian J
- Braun, Frédérique
- Letai, Anthony
- Tait, Stephen W G
- Gautier, Fabien
- Juin, Philippe P
Producer: 20171120
In:
Cell reports vol. 17
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Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy. [electronic resource] by
- Montero, Joan
- Sarosiek, Kristopher A
- DeAngelo, Joseph D
- Maertens, Ophélia
- Ryan, Jeremy
- Ercan, Dalia
- Piao, Huiying
- Horowitz, Neil S
- Berkowitz, Ross S
- Matulonis, Ursula
- Jänne, Pasi A
- Amrein, Philip C
- Cichowski, Karen
- Drapkin, Ronny
- Letai, Anthony
Producer: 20150429
In:
Cell vol. 160
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BCL-X [electronic resource] by
- Carné Trécesson, Sophie de
- Souazé, Frédérique
- Basseville, Agnès
- Bernard, Anne-Charlotte
- Pécot, Jessie
- Lopez, Jonathan
- Bessou, Margaux
- Sarosiek, Kristopher A
- Letai, Anthony
- Barillé-Nion, Sophie
- Valo, Isabelle
- Coqueret, Olivier
- Guette, Catherine
- Campone, Mario
- Gautier, Fabien
- Juin, Philippe Paul
Producer: 20180927
In:
Nature communications vol. 8
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29.
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Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance. [electronic resource] by
- Johnson, Neil
- Johnson, Shawn F
- Yao, Wei
- Li, Yu-Chen
- Choi, Young-Eun
- Bernhardy, Andrea J
- Wang, Yifan
- Capelletti, Marzia
- Sarosiek, Kristopher A
- Moreau, Lisa A
- Chowdhury, Dipanjan
- Wickramanayake, Anneka
- Harrell, Maria I
- Liu, Joyce F
- D'Andrea, Alan D
- Miron, Alexander
- Swisher, Elizabeth M
- Shapiro, Geoffrey I
Producer: 20131209
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 110
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Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics. [electronic resource] by
- Sarosiek, Kristopher A
- Fraser, Cameron
- Muthalagu, Nathiya
- Bhola, Patrick D
- Chang, Weiting
- McBrayer, Samuel K
- Cantlon, Adam
- Fisch, Sudeshna
- Golomb-Mello, Gail
- Ryan, Jeremy A
- Deng, Jing
- Jian, Brian
- Corbett, Chris
- Goldenberg, Marti
- Madsen, Joseph R
- Liao, Ronglih
- Walsh, Dominic
- Sedivy, John
- Murphy, Daniel J
- Carrasco, Daniel Ruben
- Robinson, Shenandoah
- Moslehi, Javid
- Letai, Anthony
Producer: 20170613
In:
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Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. [electronic resource] by
- Ni Chonghaile, Triona
- Sarosiek, Kristopher A
- Vo, Thanh-Trang
- Ryan, Jeremy A
- Tammareddi, Anupama
- Moore, Victoria Del Gaizo
- Deng, Jing
- Anderson, Kenneth C
- Richardson, Paul
- Tai, Yu-Tzu
- Mitsiades, Constantine S
- Matulonis, Ursula A
- Drapkin, Ronny
- Stone, Richard
- Deangelo, Daniel J
- McConkey, David J
- Sallan, Stephen E
- Silverman, Lewis
- Hirsch, Michelle S
- Carrasco, Daniel Ruben
- Letai, Anthony
Producer: 20121101
In:
Science (New York, N.Y.) vol. 334
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Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents. [electronic resource] by
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- Kolb, Kellie E
- Christie, Amanda L
- Van Scoyk, Alexandria
- Prakadan, Sanjay M
- Shigemori, Kay
- Stevenson, Kristen E
- Morrow, Sara
- Plana, Olivia D
- Fraser, Cameron
- Jones, Kristen L
- Liu, Huiyun
- Pallasch, Christian P
- Modiste, Rebecca
- Nguyen, Quang-De
- Craig, Jeffrey W
- Morgan, Elizabeth A
- Vega, Francisco
- Aster, Jon C
- Sarosiek, Kristopher A
- Shalek, Alex K
- Hemann, Michael T
- Weinstock, David M
Producer: 20200824
In:
Cancer discovery vol. 9
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CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer. [electronic resource] by
- Johnson, Shawn F
- Cruz, Cristina
- Greifenberg, Ann Katrin
- Dust, Sofia
- Stover, Daniel G
- Chi, David
- Primack, Benjamin
- Cao, Shiliang
- Bernhardy, Andrea J
- Coulson, Rhiannon
- Lazaro, Jean-Bernard
- Kochupurakkal, Bose
- Sun, Heather
- Unitt, Christine
- Moreau, Lisa A
- Sarosiek, Kristopher A
- Scaltriti, Maurizio
- Juric, Dejan
- Baselga, José
- Richardson, Andrea L
- Rodig, Scott J
- D'Andrea, Alan D
- Balmaña, Judith
- Johnson, Neil
- Geyer, Matthias
- Serra, Violeta
- Lim, Elgene
- Shapiro, Geoffrey I
Producer: 20171121
In:
Cell reports vol. 17
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Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. [electronic resource] by
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- Mayers, Jared R
- DiNatale, Gabriel J
- Shi, Diana D
- Khanal, Januka
- Chakraborty, Abhishek A
- Sarosiek, Kristopher A
- Briggs, Kimberly J
- Robbins, Alissa K
- Sewastianik, Tomasz
- Shareef, Sarah J
- Olenchock, Benjamin A
- Parker, Seth J
- Tateishi, Kensuke
- Spinelli, Jessica B
- Islam, Mirazul
- Haigis, Marcia C
- Looper, Ryan E
- Ligon, Keith L
- Bernstein, Bradley E
- Carrasco, Ruben D
- Cahill, Daniel P
- Asara, John M
- Metallo, Christian M
- Yennawar, Neela H
- Vander Heiden, Matthew G
- Kaelin, William G
Producer: 20190617
In:
Cell vol. 175
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Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in [electronic resource] by
- Nangia, Varuna
- Siddiqui, Faria M
- Caenepeel, Sean
- Timonina, Daria
- Bilton, Samantha J
- Phan, Nicole
- Gomez-Caraballo, Maria
- Archibald, Hannah L
- Li, Chendi
- Fraser, Cameron
- Rigas, Diamanda
- Vajda, Kristof
- Ferris, Lorin A
- Lanuti, Michael
- Wright, Cameron D
- Raskin, Kevin A
- Cahill, Daniel P
- Shin, John H
- Keyes, Colleen
- Sequist, Lecia V
- Piotrowska, Zofia
- Farago, Anna F
- Azzoli, Christopher G
- Gainor, Justin F
- Sarosiek, Kristopher A
- Brown, Sean P
- Coxon, Angela
- Benes, Cyril H
- Hughes, Paul E
- Hata, Aaron N
Producer: 20191223
In:
Cancer discovery vol. 8
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Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer. [electronic resource] by
- Stover, Elizabeth H
- Baco, Maria B
- Cohen, Ofir
- Li, Yvonne Y
- Christie, Elizabeth L
- Bagul, Mukta
- Goodale, Amy
- Lee, Yenarae
- Pantel, Sasha
- Rees, Matthew G
- Wei, Guo
- Presser, Adam G
- Gelbard, Maya K
- Zhang, Weiqun
- Zervantonakis, Ioannis K
- Bhola, Patrick D
- Ryan, Jeremy
- Guerriero, Jennifer L
- Montero, Joan
- Liang, Felice J
- Cherniack, Andrew D
- Piccioni, Federica
- Matulonis, Ursula A
- Bowtell, David D L
- Sarosiek, Kristopher A
- Letai, Anthony
- Garraway, Levi A
- Johannessen, Cory M
- Meyerson, Matthew
Producer: 20200728
In:
Molecular cancer research : MCR vol. 17
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37.
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Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. [electronic resource] by
- Burger, Jan A
- Landau, Dan A
- Taylor-Weiner, Amaro
- Bozic, Ivana
- Zhang, Huidan
- Sarosiek, Kristopher
- Wang, Lili
- Stewart, Chip
- Fan, Jean
- Hoellenriegel, Julia
- Sivina, Mariela
- Dubuc, Adrian M
- Fraser, Cameron
- Han, Yulong
- Li, Shuqiang
- Livak, Kenneth J
- Zou, Lihua
- Wan, Youzhong
- Konoplev, Sergej
- Sougnez, Carrie
- Brown, Jennifer R
- Abruzzo, Lynne V
- Carter, Scott L
- Keating, Michael J
- Davids, Matthew S
- Wierda, William G
- Cibulskis, Kristian
- Zenz, Thorsten
- Werner, Lillian
- Dal Cin, Paola
- Kharchencko, Peter
- Neuberg, Donna
- Kantarjian, Hagop
- Lander, Eric
- Gabriel, Stacey
- O'Brien, Susan
- Letai, Anthony
- Weitz, David A
- Nowak, Martin A
- Getz, Gad
- Wu, Catherine J
Producer: 20180920
In:
Nature communications vol. 7
Availability: No items available.
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