Results
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21.
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B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor. [electronic resource] by
- Post-Munson, Debra J
- Pieschl, Rick L
- Molski, Thaddeus F
- Graef, John D
- Hendricson, Adam W
- Knox, Ronald J
- McDonald, Ivar M
- Olson, Richard E
- Macor, John E
- Weed, Michael R
- Bristow, Linda J
- Kiss, Laszlo
- Ahlijanian, Michael K
- Herrington, James
Producer: 20170428
In:
European journal of pharmacology vol. 799
Availability: No items available.
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22.
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Unlocking P(V): Reagents for chiral phosphorothioate synthesis. [electronic resource] by
- Knouse, Kyle W
- deGruyter, Justine N
- Schmidt, Michael A
- Zheng, Bin
- Vantourout, Julien C
- Kingston, Cian
- Mercer, Stephen E
- Mcdonald, Ivar M
- Olson, Richard E
- Zhu, Ye
- Hang, Chao
- Zhu, Jason
- Yuan, Changxia
- Wang, Qinggang
- Park, Peter
- Eastgate, Martin D
- Baran, Phil S
Producer: 20181026
In:
Science (New York, N.Y.) vol. 361
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23.
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Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists. [electronic resource] by
- McDonald, Ivar M
- Mate, Robert A
- Zusi, F Christopher
- Huang, Hong
- Post-Munson, Debra J
- Ferrante, Meredith A
- Gallagher, Lizbeth
- Bertekap, Robert L
- Knox, Ronald J
- Robertson, Barbara J
- Harden, David G
- Morgan, Daniel G
- Lodge, Nicholas J
- Dworetzky, Steven I
- Olson, Richard E
- Macor, John E
Producer: 20130903
In:
Bioorganic & medicinal chemistry letters vol. 23
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24.
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Imidazo[4,5-b]pyridines as corticotropin releasing factor receptor ligands. [electronic resource] by
- Arvanitis, Argyrios G
- Rescinito, Joseph T
- Arnold, Charles R
- Wilde, Richard G
- Cain, Gary A
- Sun, Jung Hui
- Yan, Jia-Sheng
- Teleha, Christopher A
- Fitzgerald, Lawrence W
- McElroy, John
- Zaczek, Robert
- Hartig, Paul R
- Grossman, Scott
- Arneric, Stephen P
- Gilligan, Paul J
- Olson, Richard E
- Robertson, David W
Producer: 20030617
In:
Bioorganic & medicinal chemistry letters vol. 13
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25.
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Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR. [electronic resource] by
- Iwuagwu, Christiana
- King, Dalton
- McDonald, Ivar M
- Cook, James
- Zusi, F Christopher
- Hill, Matthew D
- Mate, Robert A
- Fang, Haiquan
- Knox, Ronald
- Gallagher, Lizbeth
- Post-Munson Amy Easton, Debra
- Miller, Regina
- Benitex, Yulia
- Siuciak, Judy
- Lodge, Nicholas
- Zaczek, Robert
- Morgan, Daniel
- Bristow, Linda
- Macor, John E
- Olson, Richard E
Producer: 20171017
In:
Bioorganic & medicinal chemistry letters vol. 27
Availability: No items available.
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26.
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Synthesis and evaluation of succinoyl-caprolactam gamma-secretase inhibitors. [electronic resource] by
- Thompson, Lorin A
- Liauw, Ann Y
- Ramanjulu, Mercy M
- Kasireddy-Polam, Padmaja
- Mercer, Stephen E
- Maduskuie, Thomas P
- Glicksman, Marcie
- Roach, Arthur H
- Meredith, Jere E
- Liu, Rui-Qin
- Combs, Andrew P
- Higaki, Jeffrey N
- Cordell, Barbara
- Seiffert, Dietmar
- Zaczek, Robert C
- Robertson, David W
- Olson, Richard E
Producer: 20060626
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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27.
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Allele-Selective Knockdown of MYH7 Using Antisense Oligonucleotides. [electronic resource] by
- Anderson, Brian R
- Jensen, Marianne L
- Hagedorn, Peter H
- Little, Sean C
- Olson, Richard E
- Ammar, Ron
- Kienzle, Bernadette
- Thompson, John
- McDonald, Ivar
- Mercer, Stephen
- Vikesaa, Jonas
- Nordbo, Bettina
- Iben, Larry
- Cao, Yang
- Natale, Joanne
- Dalton-Kay, Greg
- Cacace, Angela
- Hansen, Bo R
- Hedtjärn, Maj
- Koch, Troels
- Bristow, Linda J
Publication details: Molecular therapy. Nucleic acids Mar 2020
In:
Molecular therapy. Nucleic acids vol. 19
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28.
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4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors. [electronic resource] by
- Pechulis, Anthony D
- Beck, James P
- Curry, Matt A
- Wolf, Mark A
- Harms, Arthur E
- Xi, Ning
- Opalka, Chet
- Sweet, Mark P
- Yang, Zhicai
- Vellekoop, A Samuel
- Klos, Andrew M
- Crocker, Peter J
- Hassler, Carla
- Laws, Mia
- Kitchen, Douglas B
- Smith, Mark A
- Olson, Richard E
- Liu, Shuang
- Molino, Bruce F
Producer: 20130423
In:
Bioorganic & medicinal chemistry letters vol. 22
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29.
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Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE). [electronic resource] by
- Boy, Kenneth M
- Guernon, Jason M
- Wu, Yong-Jin
- Zhang, Yunhui
- Shi, Joe
- Zhai, Weixu
- Zhu, Shirong
- Gerritz, Samuel W
- Toyn, Jeremy H
- Meredith, Jere E
- Barten, Donna M
- Burton, Catherine R
- Albright, Charles F
- Good, Andrew C
- Grace, James E
- Lentz, Kimberley A
- Olson, Richard E
- Macor, John E
- Thompson, Lorin A
Producer: 20160811
In:
Bioorganic & medicinal chemistry letters vol. 25
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30.
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Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents. [electronic resource] by
- Pieschl, Rick L
- Miller, Regina
- Jones, Kelli M
- Post-Munson, Debra J
- Chen, Ping
- Newberry, Kimberly
- Benitex, Yulia
- Molski, Thaddeus
- Morgan, Daniel
- McDonald, Ivar M
- Macor, John E
- Olson, Richard E
- Asaka, Yukiko
- Digavalli, Siva
- Easton, Amy
- Herrington, James
- Westphal, Ryan S
- Lodge, Nicholas J
- Zaczek, Robert
- Bristow, Linda J
- Li, Yu-Wen
Producer: 20171205
In:
European journal of pharmacology vol. 807
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31.
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Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE). [electronic resource] by
- Boy, Kenneth M
- Guernon, Jason M
- Shi, Jianliang
- Toyn, Jeremy H
- Meredith, Jere E
- Barten, Donna M
- Burton, Catherine R
- Albright, Charles F
- Marcinkeviciene, Jovita
- Good, Andrew C
- Tebben, Andrew J
- Muckelbauer, Jodi K
- Camac, Daniel M
- Lentz, Kimberley A
- Bronson, Joanne J
- Olson, Richard E
- Macor, John E
- Thompson, Lorin A
Producer: 20120213
In:
Bioorganic & medicinal chemistry letters vol. 21
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32.
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The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers. [electronic resource] by
- Soares, Holly D
- Gasior, Maciej
- Toyn, Jeremy H
- Wang, Jun-Sheng
- Hong, Quan
- Berisha, Flora
- Furlong, Michael T
- Raybon, Joseph
- Lentz, Kimberley A
- Sweeney, Francis
- Zheng, Naiyu
- Akinsanya, Billy
- Berman, Robert M
- Thompson, Lorin A
- Olson, Richard E
- Morrison, John
- Drexler, Dieter M
- Macor, John E
- Albright, Charlie F
- Ahlijanian, Michael K
- AbuTarif, Malaz
Producer: 20170523
In:
The Journal of pharmacology and experimental therapeutics vol. 358
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33.
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P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice. [electronic resource] by
- Meredith, Jere E
- Thompson, Lorin A
- Toyn, Jeremy H
- Marcin, Lawrence
- Barten, Donna M
- Marcinkeviciene, Jovita
- Kopcho, Lisa
- Kim, Young
- Lin, Alan
- Guss, Valerie
- Burton, Catherine
- Iben, Lawrence
- Polson, Craig
- Cantone, Joe
- Ford, Michael
- Drexler, Dieter
- Fiedler, Tracey
- Lentz, Kimberley A
- Grace, James E
- Kolb, Janet
- Corsa, Jason
- Pierdomenico, Maria
- Jones, Kelli
- Olson, Richard E
- Macor, John E
- Albright, Charles F
Producer: 20080812
In:
The Journal of pharmacology and experimental therapeutics vol. 326
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34.
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Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor. [electronic resource] by
- Gillman, Kevin W
- Starrett, John E
- Parker, Michael F
- Xie, Kai
- Bronson, Joanne J
- Marcin, Lawrence R
- McElhone, Kate E
- Bergstrom, Carl P
- Mate, Robert A
- Williams, Richard
- Meredith, Jere E
- Burton, Catherine R
- Barten, Donna M
- Toyn, Jeremy H
- Roberts, Susan B
- Lentz, Kimberley A
- Houston, John G
- Zaczek, Robert
- Albright, Charles F
- Decicco, Carl P
- Macor, John E
- Olson, Richard E
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 1
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35.
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Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027. [electronic resource] by
- Barten, Donna M
- Fanara, Patrizia
- Andorfer, Cathy
- Hoque, Nina
- Wong, P Y Anne
- Husted, Kristofor H
- Cadelina, Gregory W
- Decarr, Lynn B
- Yang, Ling
- Liu, Victoria
- Fessler, Chancy
- Protassio, Joan
- Riff, Timothy
- Turner, Holly
- Janus, Christopher G
- Sankaranarayanan, Sethu
- Polson, Craig
- Meredith, Jere E
- Gray, Gemma
- Hanna, Amanda
- Olson, Richard E
- Kim, Soong-Hoon
- Vite, Gregory D
- Lee, Francis Y
- Albright, Charles F
Producer: 20120803
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 32
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36.
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In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists. [electronic resource] by
- Hartz, Richard A
- Ahuja, Vijay T
- Rafalski, Maria
- Schmitz, William D
- Brenner, Allison B
- Denhart, Derek J
- Ditta, Jonathan L
- Deskus, Jeffrey A
- Yue, Eddy W
- Arvanitis, Argyrios G
- Lelas, Snjezana
- Li, Yu-Wen
- Molski, Thaddeus F
- Wong, Harvey
- Grace, James E
- Lentz, Kimberley A
- Li, Jianqing
- Lodge, Nicholas J
- Zaczek, Robert
- Combs, Andrew P
- Olson, Richard E
- Mattson, Ronald J
- Bronson, Joanne J
- Macor, John E
Producer: 20090825
In:
Journal of medicinal chemistry vol. 52
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37.
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BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia. [electronic resource] by
- King, Dalton
- Iwuagwu, Christiana
- Cook, Jim
- McDonald, Ivar M
- Mate, Robert
- Zusi, F Christopher
- Hill, Matthew D
- Fang, Haiquan
- Zhao, Rulin
- Wang, Bei
- Easton, Amy E
- Miller, Regina
- Post-Munson, Debra
- Knox, Ronald J
- Gallagher, Lizbeth
- Westphal, Ryan
- Molski, Thaddeus
- Fan, Jingsong
- Clarke, Wendy
- Benitex, Yulia
- Lentz, Kimberley A
- Denton, Rex
- Morgan, Daniel
- Zaczek, Robert
- Lodge, Nicholas J
- Bristow, Linda J
- Macor, John E
- Olson, Richard E
Publication details: ACS medicinal chemistry letters Mar 2017
In:
ACS medicinal chemistry letters vol. 8
Availability: No items available.
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38.
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Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitors. [electronic resource] by
- Thompson, Lorin A
- Shi, Jianliang
- Decicco, Carl P
- Tebben, Andrew J
- Olson, Richard E
- Boy, Kenneth M
- Guernon, Jason M
- Good, Andrew C
- Liauw, Ann
- Zheng, Changsheng
- Copeland, Robert A
- Combs, Andrew P
- Trainor, George L
- Camac, Daniel M
- Muckelbauer, Jodi K
- Lentz, Kimberley A
- Grace, James E
- Burton, Catherine R
- Toyn, Jeremy H
- Barten, Donna M
- Marcinkeviciene, Jovita
- Meredith, Jere E
- Albright, Charles F
- Macor, John E
Producer: 20120213
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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39.
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Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481. [electronic resource] by
- Boy, Kenneth M
- Guernon, Jason M
- Zuev, Dmitry S
- Xu, Li
- Zhang, Yunhui
- Shi, Jianliang
- Marcin, Lawrence R
- Higgins, Mendi A
- Wu, Yong-Jin
- Krishnananthan, Subramaniam
- Li, Jianqing
- Trehan, Ashok
- Smith, Daniel
- Toyn, Jeremy H
- Meredith, Jere E
- Burton, Catherine R
- Kimura, S Roy
- Zvyaga, Tatyana
- Zhuo, Xiaoliang
- Lentz, Kimberley A
- Grace, James E
- Denton, Rex
- Morrison, John S
- Mathur, Arvind
- Albright, Charles F
- Ahlijanian, Michael K
- Olson, Richard E
- Thompson, Lorin A
- Macor, John E
Publication details: ACS medicinal chemistry letters Mar 2019
In:
ACS medicinal chemistry letters vol. 10
Availability: No items available.
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40.
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Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects. [electronic resource] by
- Toyn, Jeremy H
- Boy, Kenneth M
- Raybon, Joseph
- Meredith, Jere E
- Robertson, Alan S
- Guss, Valerie
- Hoque, Nina
- Sweeney, Francis
- Zhuo, Xiaoliang
- Clarke, Wendy
- Snow, Kimberly
- Denton, R Rex
- Zuev, Dmitry
- Thompson, Lorin A
- Morrison, John
- Grace, James
- Berisha, Flora
- Furlong, Michael
- Wang, Jun-Sheng
- Lentz, Kimberly A
- Padmanabha, Ramesh
- Cook, Lynda
- Wei, Cong
- Drexler, Dieter M
- Macor, John E
- Albright, Charlie F
- Gasior, Maciej
- Olson, Richard E
- Hong, Quan
- Soares, Holly D
- AbuTarif, Malaz
- Ahlijanian, Michael K
Producer: 20170523
In:
The Journal of pharmacology and experimental therapeutics vol. 358
Availability: No items available.
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