Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE). [electronic resource]
Producer: 20160811Description: 5040-7 p. digitalISSN:- 1464-3405
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Amyloid beta-Peptides -- biosynthesis
- Animals
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Caco-2 Cells
- Cathepsin D -- antagonists & inhibitors
- Cathepsin E -- antagonists & inhibitors
- Dogs
- Guanidines -- chemical synthesis
- Humans
- Macrocyclic Compounds -- chemical synthesis
- Madin Darby Canine Kidney Cells
- Male
- Mice
- Molecular Docking Simulation
- Pepsin A -- antagonists & inhibitors
- Proline -- analogs & derivatives
- Protease Inhibitors -- chemical synthesis
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Publication Type: Journal Article
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