Synthesis and evaluation of succinoyl-caprolactam gamma-secretase inhibitors. [electronic resource]
Producer: 20060626Description: 2357-63 p. digitalISSN:- 0960-894X
- Alzheimer Disease -- drug therapy
- Amyloid Precursor Protein Secretases
- Animals
- Aspartic Acid Endopeptidases
- Caprolactam -- analogs & derivatives
- Cell Line
- Dogs
- Drug Design
- Drug Evaluation, Preclinical
- Endopeptidases -- chemistry
- Enzyme Inhibitors -- chemical synthesis
- Humans
- Molecular Conformation
- Stereoisomerism
- Structure-Activity Relationship
- Succinates -- chemistry
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Publication Type: Journal Article
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