Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach. [electronic resource]
Producer: 20210512Description: 127174 p. digitalISSN:- 1464-3405
- Administration, Oral
- Amides -- administration & dosage
- Animals
- Dose-Response Relationship, Drug
- Drug Discovery
- Microsomes, Liver -- chemistry
- Molecular Structure
- Nuclear Receptor Subfamily 1, Group F, Member 3 -- agonists
- Oxadiazoles -- administration & dosage
- Rats
- Structure-Activity Relationship
- Thiazoles -- administration & dosage
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Publication Type: Journal Article
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