Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach. (Record no. 30901011)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01788 a2200505 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518100707.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202105s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1464-3405 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2020.127174 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Steeneck, Christoph |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20210512 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | 06 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 127174 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amides |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Microsomes, Liver |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Structure |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nuclear Receptor Subfamily 1, Group F, Member 3 |
| General subdivision | agonists |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oxadiazoles |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Thiazoles |
| General subdivision | administration & dosage |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gege, Christian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kinzel, Olaf |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Albers, Michael |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kleymann, Gerald |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schlüter, Thomas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schulz, Andreas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xue, Xiaohua |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cummings, Maxwell D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fourie, Anne M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leonard, Kristi A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Scott, Brian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Edwards, James P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hoffmann, Thomas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Goldberg, Steven D |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 30 |
| -- | no. 12 |
| -- | p. 127174 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2020.127174">https://doi.org/10.1016/j.bmcl.2020.127174</a> |
| Public note | Available from publisher's website |
No items available.