Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors. [electronic resource]
Producer: 20181005Description: 1727-1739 p. digitalISSN:- 1464-3391
- Dose-Response Relationship, Drug
- Drug Discovery
- Enzyme Inhibitors -- chemical synthesis
- High-Throughput Screening Assays
- Humans
- Molecular Structure
- Phosphoglycerate Dehydrogenase -- antagonists & inhibitors
- Piperazines -- chemical synthesis
- Structure-Activity Relationship
- Thiourea -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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