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  2. Details for: Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.
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Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. [electronic resource]

By:
  • Deng, Gejing
Contributor(s):
  • Shen, Junqing
  • Yin, Ming
  • McManus, Jessica
  • Mathieu, Magali
  • Gee, Patricia
  • He, Timothy
  • Shi, Chaomei
  • Bedel, Olivier
  • McLean, Larry R
  • Le-Strat, Frank
  • Zhang, Ying
  • Marquette, Jean-Pierre
  • Gao, Qiang
  • Zhang, Bailin
  • Rak, Alexey
  • Hoffmann, Dietmar
  • Rooney, Eamonn
  • Vassort, Aurelie
  • Englaro, Walter
  • Li, Yi
  • Patel, Vinod
  • Adrian, Francisco
  • Gross, Stefan
  • Wiederschain, Dmitri
  • Cheng, Hong
  • Licht, Stuart
Producer: 20150421Description: 762-74 p. digitalISSN:
  • 1083-351X
Subject(s):
  • Allosteric Site
  • Crystallography, X-Ray
  • DNA Methylation -- genetics
  • Drug Discovery
  • Enzyme Inhibitors -- chemical synthesis
  • Escherichia coli
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Isocitrate Dehydrogenase -- antagonists & inhibitors
  • Magnesium -- chemistry
  • Mutant Proteins -- chemistry
  • Neoplasms -- drug therapy
  • Protein Conformation
Online resources:
  • Available from publisher's website
In: The Journal of biological chemistry vol. 290
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Publication Type: Journal Article

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Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.

APA

Deng G., Shen J., Yin M., McManus J., Mathieu M., Gee P., He T., Shi C., Bedel O., McLean L. R., Le-Strat F., Zhang Y., Marquette J., Gao Q., Zhang B., Rak A., Hoffmann D., Rooney E., Vassort A., Englaro W., Li Y., Patel V., Adrian F., Gross S., Wiederschain D., Cheng H. & Licht S. (20150421). Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. : The Journal of biological chemistry.

Chicago

Deng Gejing, Shen Junqing, Yin Ming, McManus Jessica, Mathieu Magali, Gee Patricia, He Timothy, Shi Chaomei, Bedel Olivier, McLean Larry R, Le-Strat Frank, Zhang Ying, Marquette Jean-Pierre, Gao Qiang, Zhang Bailin, Rak Alexey, Hoffmann Dietmar, Rooney Eamonn, Vassort Aurelie, Englaro Walter, Li Yi, Patel Vinod, Adrian Francisco, Gross Stefan, Wiederschain Dmitri, Cheng Hong and Licht Stuart. 20150421. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. : The Journal of biological chemistry.

Harvard

Deng G., Shen J., Yin M., McManus J., Mathieu M., Gee P., He T., Shi C., Bedel O., McLean L. R., Le-Strat F., Zhang Y., Marquette J., Gao Q., Zhang B., Rak A., Hoffmann D., Rooney E., Vassort A., Englaro W., Li Y., Patel V., Adrian F., Gross S., Wiederschain D., Cheng H. and Licht S. (20150421). Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. : The Journal of biological chemistry.

MLA

Deng Gejing, Shen Junqing, Yin Ming, McManus Jessica, Mathieu Magali, Gee Patricia, He Timothy, Shi Chaomei, Bedel Olivier, McLean Larry R, Le-Strat Frank, Zhang Ying, Marquette Jean-Pierre, Gao Qiang, Zhang Bailin, Rak Alexey, Hoffmann Dietmar, Rooney Eamonn, Vassort Aurelie, Englaro Walter, Li Yi, Patel Vinod, Adrian Francisco, Gross Stefan, Wiederschain Dmitri, Cheng Hong and Licht Stuart. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. : The Journal of biological chemistry. 20150421.

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