Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. (Record no. 24349432)

MARC details
000 -LEADER
fixed length control field 02125 a2200661 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250517002520.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201504s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1083-351X
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1074/jbc.M114.608497
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Deng, Gejing
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20150421
245 00 - TITLE STATEMENT
Title Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. The Journal of biological chemistry
Date of publication, distribution, etc. Jan 2015
300 ## - PHYSICAL DESCRIPTION
Extent 762-74 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Allosteric Site
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Crystallography, X-Ray
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DNA Methylation
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Discovery
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Enzyme Inhibitors
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Escherichia coli
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Gene Expression Regulation, Neoplastic
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Isocitrate Dehydrogenase
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Magnesium
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mutant Proteins
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neoplasms
General subdivision drug therapy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Conformation
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Shen, Junqing
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yin, Ming
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name McManus, Jessica
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mathieu, Magali
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gee, Patricia
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name He, Timothy
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Shi, Chaomei
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bedel, Olivier
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name McLean, Larry R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Le-Strat, Frank
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Ying
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Marquette, Jean-Pierre
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gao, Qiang
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Bailin
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rak, Alexey
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hoffmann, Dietmar
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rooney, Eamonn
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Vassort, Aurelie
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Englaro, Walter
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Li, Yi
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Patel, Vinod
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Adrian, Francisco
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gross, Stefan
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wiederschain, Dmitri
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Cheng, Hong
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Licht, Stuart
773 0# - HOST ITEM ENTRY
Title The Journal of biological chemistry
Related parts vol. 290
-- no. 2
-- p. 762-74
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1074/jbc.M114.608497">https://doi.org/10.1074/jbc.M114.608497</a>
Public note Available from publisher's website

No items available.