Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production. [electronic resource]
Producer: 20121207Description: 32640-50 p. digitalISSN:- 1083-351X
- Amyloid -- genetics
- Amyloid Precursor Protein Secretases -- genetics
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Female
- Flurbiprofen -- pharmacology
- HEK293 Cells
- Humans
- Mice
- Protein Processing, Post-Translational -- drug effects
- Protein Structure, Tertiary
- Receptors, Notch -- genetics
- Sulindac -- analogs & derivatives
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Publication Type: Journal Article
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