Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production. (Record no. 21990462)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01790 a2200517 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516104006.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201212s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1083-351X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1074/jbc.M112.376541 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Wanngren, Johanna |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20121207 |
| 245 00 - TITLE STATEMENT | |
| Title | Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | The Journal of biological chemistry |
| Date of publication, distribution, etc. | Sep 2012 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 32640-50 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid Precursor Protein Secretases |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid beta-Protein Precursor |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anti-Inflammatory Agents, Non-Steroidal |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Flurbiprofen |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Processing, Post-Translational |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Structure, Tertiary |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Notch |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulindac |
| General subdivision | analogs & derivatives |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ottervald, Jan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Parpal, Santiago |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Portelius, Erik |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Strömberg, Kia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Borgegård, Tomas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Klintenberg, Rebecka |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Juréus, Anders |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Blomqvist, Jenny |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Blennow, Kaj |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zetterberg, Henrik |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lundkvist, Johan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rosqvist, Susanne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Karlström, Helena |
| 773 0# - HOST ITEM ENTRY | |
| Title | The Journal of biological chemistry |
| Related parts | vol. 287 |
| -- | no. 39 |
| -- | p. 32640-50 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1074/jbc.M112.376541">https://doi.org/10.1074/jbc.M112.376541</a> |
| Public note | Available from publisher's website |
No items available.