Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations. (Record no. 28577369)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02572 a2200805 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517224255.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201812s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1476-4687 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/s41586-018-0251-7 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Intlekofer, Andrew M |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20181211 |
| 245 00 - TITLE STATEMENT | |
| Title | Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature |
| Date of publication, distribution, etc. | 07 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 125-129 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alleles |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Allosteric Site |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aminopyridines |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Clinical Trials, Phase I as Topic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Clinical Trials, Phase II as Topic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Progression |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Neoplasm |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Inhibitors |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Glutamine |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Glutarates |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Isocitrate Dehydrogenase |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Isoleucine |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia, Myeloid, Acute |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutant Proteins |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Multimerization |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Triazines |
| General subdivision | chemistry |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shih, Alan H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Bo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nazir, Abbas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rustenburg, Ariën S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Albanese, Steven K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patel, Minal |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Famulare, Christopher |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Correa, Fabian M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Takemoto, Naofumi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Durani, Vidushi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, Hui |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Taylor, Justin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Farnoud, Noushin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Papaemmanuil, Elli |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cross, Justin R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tallman, Martin S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Arcila, Maria E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Roshal, Mikhail |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Petsko, Gregory A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wu, Bin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Choe, Sung |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Konteatis, Zenon D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Biller, Scott A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chodera, John D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thompson, Craig B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Levine, Ross L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stein, Eytan M |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature |
| Related parts | vol. 559 |
| -- | no. 7712 |
| -- | p. 125-129 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/s41586-018-0251-7">https://doi.org/10.1038/s41586-018-0251-7</a> |
| Public note | Available from publisher's website |
No items available.