Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance Mechanisms. (Record no. 26552875)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01862 a2200541 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517122629.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201802s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1521-009X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1124/dmd.116.072983 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Leung, Louis |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20180221 |
| 245 00 - TITLE STATEMENT | |
| Title | Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance Mechanisms. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Drug metabolism and disposition: the biological fate of chemicals |
| Date of publication, distribution, etc. | 01 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1-7 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Algorithms |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Evaluation, Preclinical |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Glutathione |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hepatocytes |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | In Vitro Techniques |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Metabolic Clearance Rate |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Microsomes, Liver |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Biological |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmaceutical Preparations |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Plasma |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Predictive Value of Tests |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Binding |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Species Specificity |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yang, Xin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Strelevitz, Timothy J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Montgomery, Justin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brown, Matthew F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zientek, Michael A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Banfield, Christopher |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gilbert, Adam M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thorarensen, Atli |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dowty, Martin E |
| 773 0# - HOST ITEM ENTRY | |
| Title | Drug metabolism and disposition: the biological fate of chemicals |
| Related parts | vol. 45 |
| -- | no. 1 |
| -- | p. 1-7 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1124/dmd.116.072983">https://doi.org/10.1124/dmd.116.072983</a> |
| Public note | Available from publisher's website |
No items available.