IBI302, a promising candidate for AMD treatment, targeting both the VEGF and complement system with high binding affinity in vitro and effective targeting of the ocular tissue in healthy rhesus monkeys. (Record no. 25774043)
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fixed length control field | 01778 a2200433 4500 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250517082540.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 201706s 0 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 1096-0007 |
024 7# - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.1016/j.exer.2016.02.004 |
Source of number or code | doi |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | NLM |
Language of cataloging | eng |
Transcribing agency | NLM |
100 1# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Ren, Xinyi |
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
Date of production, publication, distribution, manufacture, or copyright notice | 20170613 |
245 00 - TITLE STATEMENT | |
Title | IBI302, a promising candidate for AMD treatment, targeting both the VEGF and complement system with high binding affinity in vitro and effective targeting of the ocular tissue in healthy rhesus monkeys. |
Medium | [electronic resource] |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Name of publisher, distributor, etc. | Experimental eye research |
Date of publication, distribution, etc. | 04 2016 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 352-358 p. |
Other physical details | digital |
500 ## - GENERAL NOTE | |
General note | Publication Type: Journal Article |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Angiogenesis Inhibitors |
General subdivision | pharmacokinetics |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Animals |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Antibodies, Monoclonal, Humanized |
General subdivision | therapeutic use |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Cell Proliferation |
General subdivision | drug effects |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Complement Activation |
General subdivision | drug effects |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Complement Inactivating Agents |
General subdivision | pharmacokinetics |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Complement System Proteins |
General subdivision | metabolism |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Human Umbilical Vein Endothelial Cells |
General subdivision | drug effects |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Humans |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Immunoglobulin Fc Fragments |
General subdivision | pharmacology |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Intravitreal Injections |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Macaca mulatta |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Macular Degeneration |
General subdivision | drug therapy |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Recombinant Fusion Proteins |
General subdivision | pharmacokinetics |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Vascular Endothelial Growth Factor A |
General subdivision | antagonists & inhibitors |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Vitreous Body |
General subdivision | metabolism |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Li, Jia |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Xu, Xianxing |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Wang, Chunming |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Cheng, Yuanguo |
773 0# - HOST ITEM ENTRY | |
Title | Experimental eye research |
Related parts | vol. 145 |
-- | p. 352-358 |
856 40 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.exer.2016.02.004">https://doi.org/10.1016/j.exer.2016.02.004</a> |
Public note | Available from publisher's website |
No items available.