Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ. (Record no. 24309728)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02055 a2200601 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517001223.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201503s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1476-5578 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/mp.2014.135 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Knight, E M |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20150330 |
| 245 00 - TITLE STATEMENT | |
| Title | Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Molecular psychiatry |
| Date of publication, distribution, etc. | Feb 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 109-17 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alzheimer Disease |
| General subdivision | complications |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid beta-Peptides |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid beta-Protein Precursor |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antipsychotic Agents |
| General subdivision | therapeutic use |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Blood-Testis Barrier |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cells, Cultured |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cognition Disorders |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Models, Animal |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Fibroblasts |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gangliosides |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Maze Learning |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Recognition, Psychology |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Time Factors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | beta-N-Acetylhexosaminidases |
| General subdivision | metabolism |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Williams, H N |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stevens, A C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, S H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kottwitz, J C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Morant, A D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Steele, J W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Klein, W L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yanagisawa, K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boyd, R E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lockhart, D J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sjoberg, E R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ehrlich, M E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wustman, B A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gandy, S |
| 773 0# - HOST ITEM ENTRY | |
| Title | Molecular psychiatry |
| Related parts | vol. 20 |
| -- | no. 1 |
| -- | p. 109-17 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/mp.2014.135">https://doi.org/10.1038/mp.2014.135</a> |
| Public note | Available from publisher's website |
No items available.