Alpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE). (Record no. 17741176)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01918 a2200529 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515105321.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200805s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1464-3405 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2008.01.030 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ott, Gregory R |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20080512 |
| 245 00 - TITLE STATEMENT | |
| Title | Alpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE). |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | Feb 2008 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1288-92 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ADAM Proteins |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ADAM17 Protein |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alkanes |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological Availability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Caco-2 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hydroxamic Acids |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Matrix Metalloproteinase Inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Matrix Metalloproteinases |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protease Inhibitors |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Spiro Compounds |
| General subdivision | chemical synthesis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Asakawa, Naoyuki |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, Rui-Qin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Covington, Maryanne B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Qian, Mingxin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vaddi, Krishna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Newton, Robert C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Trzaskos, James M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Christ, David D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Galya, Laurine |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Scholz, Thomas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marshall, Will |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Duan, James J-W |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 18 |
| -- | no. 4 |
| -- | p. 1288-92 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2008.01.030">https://doi.org/10.1016/j.bmcl.2008.01.030</a> |
| Public note | Available from publisher's website |
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