Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles. (Record no. 10369660)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02527 a2200817 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250513185811.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 199908s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0022-3565 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Chan, C C |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 19990818 |
| 245 00 - TITLE STATEMENT | |
| Title | Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | The Journal of pharmacology and experimental therapeutics |
| Date of publication, distribution, etc. | Aug 1999 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 551-60 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Arachidonate 15-Lipoxygenase |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Arachidonic Acid |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Arthritis, Experimental |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Blood Platelets |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | COS Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cricetinae |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cyclooxygenase 2 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cyclooxygenase 2 Inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cyclooxygenase Inhibitors |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Digestive System |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Edema |
| General subdivision | chemically induced |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hyperalgesia |
| General subdivision | chemically induced |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | In Vitro Techniques |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Isoenzymes |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Lactones |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukotriene B4 |
| General subdivision | biosynthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Membrane Proteins |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Microsomes |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Prostaglandin-Endoperoxide Synthases |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Inbred Lew |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Saimiri |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulfones |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boyce, S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brideau, C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Charleson, S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cromlish, W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ethier, D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Evans, J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ford-Hutchinson, A W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Forrest, M J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gauthier, J Y |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gordon, R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gresser, M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Guay, J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kargman, S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kennedy, B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leblanc, Y |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leger, S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mancini, J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | O'Neill, G P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ouellet, M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patrick, D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Percival, M D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Perrier, H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Prasit, P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rodger, I |
| 773 0# - HOST ITEM ENTRY | |
| Title | The Journal of pharmacology and experimental therapeutics |
| Related parts | vol. 290 |
| -- | no. 2 |
| -- | p. 551-60 |
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