Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency. [electronic resource]
Producer: 20100916Description: 5942-55 p. digitalISSN:- 1520-4804
- Aminopyridines -- chemical synthesis
- Antineoplastic Agents -- chemistry
- Crystallography, X-Ray
- Databases, Factual
- Drug Design
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Ligands
- Magnetic Resonance Spectroscopy
- Models, Molecular
- Phenols -- chemical synthesis
- Protein Binding
- Protein Structure, Tertiary
- Resorcinols -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article
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