Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency. (Record no. 20054553)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01900 a2200565 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515235000.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201009s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm100059d |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Murray, Christopher W |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20100916 |
| 245 00 - TITLE STATEMENT | |
| Title | Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Aug 2010 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 5942-55 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aminopyridines |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Crystallography, X-Ray |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Databases, Factual |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Design |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HSP90 Heat-Shock Proteins |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ligands |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Magnetic Resonance Spectroscopy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phenols |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Binding |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Structure, Tertiary |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Resorcinols |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Carr, Maria G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Callaghan, Owen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chessari, Gianni |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Congreve, Miles |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cowan, Suzanna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Coyle, Joseph E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Downham, Robert |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Figueroa, Eva |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Frederickson, Martyn |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Graham, Brent |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McMenamin, Rachel |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | O'Brien, M Alistair |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patel, Sahil |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Phillips, Theresa R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Williams, Glyn |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Woodhead, Andrew J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Woolford, Alison J-A |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 53 |
| -- | no. 16 |
| -- | p. 5942-55 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm100059d">https://doi.org/10.1021/jm100059d</a> |
| Public note | Available from publisher's website |
No items available.