Discovery and synthesis of novel indole derivatives-containing 3-methylenedihydrofuran-2(3H)-one as irreversible LSD1 inhibitors. [electronic resource]
Producer: 20190715Description: 357-372 p. digitalISSN:- 1768-3254
- Cell Line
- Cell Proliferation -- drug effects
- Drug Discovery
- Enzyme Inhibitors -- chemical synthesis
- Furans -- chemistry
- High-Throughput Screening Assays
- Histone Demethylases -- antagonists & inhibitors
- Humans
- Indoles -- chemical synthesis
- Inhibitory Concentration 50
- Leukemia, Myeloid, Acute -- pathology
- Recombinant Proteins -- drug effects
- Structure-Activity Relationship
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Publication Type: Journal Article
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