Results
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Optimization of 2,3,5-trisubstituted pyridine derivatives as potent allosteric Akt1 and Akt2 inhibitors. [electronic resource] by
- Hartnett, John C
- Barnett, Stanley F
- Bilodeau, Mark T
- Defeo-Jones, Deborah
- Hartman, George D
- Huber, Hans E
- Jones, Raymond E
- Kral, Astrid M
- Robinson, Ronald G
- Wu, Zhicai
Producer: 20080609
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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5.
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Probing the SAR of dEpoB via chemical synthesis: a total synthesis evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B. [electronic resource] by
- Chappell, Mark D
- Harris, Christina R
- Kuduk, Scott D
- Balog, Aaron
- Wu, Zhicai
- Zhang, Fei
- Lee, Chul Bom
- Stachel, Shawn J
- Danishefsky, Samuel J
- Chou, Ting-Chao
- Guan, Yongbiao
Producer: 20040512
In:
The Journal of organic chemistry vol. 67
Availability: No items available.
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6.
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Rapid assembly of diverse and potent allosteric Akt inhibitors. [electronic resource] by
- Wu, Zhicai
- Robinson, Ronald G
- Fu, Sheng
- Barnett, Stanley F
- Defeo-Jones, Deborah
- Jones, Raymond E
- Kral, Astrid M
- Huber, Hans E
- Kohl, Nancy E
- Hartman, George D
- Bilodeau, Mark T
Producer: 20080609
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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7.
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Development of pyridopyrimidines as potent Akt1/2 inhibitors. [electronic resource] by
- Wu, Zhicai
- Hartnett, John C
- Neilson, Lou Anne
- Robinson, Ronald G
- Fu, Sheng
- Barnett, Stanley F
- Defeo-Jones, Deborah
- Jones, Raymond E
- Kral, Astrid M
- Huber, Hans E
- Hartman, George D
- Bilodeau, Mark T
Producer: 20080512
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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8.
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Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR. [electronic resource] by
- Wu, Zhicai
- Fraley, Mark E
- Bilodeau, Mark T
- Kaufman, Mildred L
- Tasber, Edward S
- Balitza, Adrienne E
- Hartman, George D
- Coll, Kathleen E
- Rickert, Keith
- Shipman, Jennifer
- Shi, Bin
- Sepp-Lorenzino, Laura
- Thomas, Kenneth A
Producer: 20040928
In:
Bioorganic & medicinal chemistry letters vol. 14
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9.
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Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists. [electronic resource] by
- Lai, Zhong
- He, Shuwen
- Sherer, Edward C
- Wu, Zhicai
- Yu, Yang
- Ball, Richard
- Hong, Qingmei
- Yang, David X
- Guo, Liangqing
- Li, Derun
- Tuang, Quang
- Chicchi, Gary G
- Trusca, Dorina
- Tsao, Kwei-Lan
- Zhou, Yun-Ping
- Howard, Andrew D
- Nargund, Ravi P
- Hagmann, William K
Producer: 20160518
In:
Bioorganic & medicinal chemistry letters vol. 25
Availability: No items available.
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10.
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Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists. [electronic resource] by
- Yang, Christine
- Shen, Hong C
- Wu, Zhicai
- Chu, Hong D
- Cox, Jason M
- Balsells, Jaume
- Crespo, Alejandro
- Brown, Patricia
- Zamlynny, Beata
- Wiltsie, Judyann
- Clemas, Joseph
- Gibson, Jack
- Contino, Lisa
- Lisnock, Jeanmarie
- Zhou, Gaochao
- Garcia-Calvo, Margarita
- Bateman, Tom
- Xu, Ling
- Tong, Xinchun
- Crook, Martin
- Sinclair, Peter
Producer: 20140124
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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11.
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Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series. [electronic resource] by
- Cox, Jason M
- Chu, Hong D
- Yang, Christine
- Shen, Hong C
- Wu, Zhicai
- Balsells, Jaume
- Crespo, Alejandro
- Brown, Patricia
- Zamlynny, Beata
- Wiltsie, Judyann
- Clemas, Joseph
- Gibson, Jack
- Contino, Lisa
- Lisnock, JeanMarie
- Zhou, Gaochao
- Garcia-Calvo, Margarita
- Bateman, Thomas
- Xu, Ling
- Tong, Xinchun
- Crook, Martin
- Sinclair, Peter
Producer: 20150330
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
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12.
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Discovery of aminoheterocycles as potent and brain penetrant prolylcarboxypeptidase inhibitors. [electronic resource] by
- Wu, Zhicai
- Yang, Cangming
- Graham, Thomas H
- Verras, Andreas
- Chabin, Renee M
- Xu, Suoyu
- Tong, Xinchun
- Xie, Dan
- Lassman, Mike E
- Bhatt, Urmi R
- Garcia-Calvo, Margarita M
- Shen, Zhu
- Chen, Qing
- Bleasby, Kelly
- Sinharoy, Ranabir
- Hale, Jeffrey J
- Tata, James R
- Pinto, Shirly
- Colletti, Steven L
- Shen, Dong-Ming
Producer: 20120531
In:
Bioorganic & medicinal chemistry letters vol. 22
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13.
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Discovery of a new class of potent prolylcarboxypeptidase inhibitors derived from alanine. [electronic resource] by
- Wu, Zhicai
- Yang, Cangming
- Xiong, Yusheng
- Feng, Zhe
- Lombardo, Matthew
- Verras, Andreas
- Chabin, Renee M
- Xu, Suoyu
- Tong, Xinchun
- Xie, Dan
- Lassman, Mike E
- Bhatt, Urmi R
- Garcia-Calvo, Margarita M
- Geissler, Wayne
- Shen, Zhu
- Chen, Qing
- Sinharoy, Ranabir
- Hale, Jeffrey J
- Tata, James R
- Pinto, Shirly
- Shen, Dong-Ming
- Colletti, Steven L
Producer: 20120531
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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14.
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Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy. [electronic resource] by
- Trotter, B Wesley
- Nanda, Kausik K
- Burgey, Christopher S
- Potteiger, Craig M
- Deng, James Z
- Green, Ahren I
- Hartnett, John C
- Kett, Nathan R
- Wu, Zhicai
- Henze, Darrell A
- Della Penna, Kimberly
- Desai, Reshma
- Leitl, Michael D
- Lemaire, Wei
- White, Rebecca B
- Yeh, Suzie
- Urban, Mark O
- Kane, Stefanie A
- Hartman, George D
- Bilodeau, Mark T
Producer: 20110719
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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15.
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Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists. [electronic resource] by
- Li, Derun
- Wu, Zhicai
- Yu, Yang
- Ball, Richard G
- Guo, Liangqin
- Sherer, Edward
- He, Shuwen
- Hong, Qingmei
- Lai, Zhong
- Qi, Hongbo
- Truong, Quang
- Yang, David X
- Chicchi, Gary G
- Tsao, Kwei-Lan
- Trusca, Dorina
- Trujillo, Maria
- Pachanski, Michele
- Eiermann, George J
- Howard, Andrew D
- Zhou, Yun-Ping
- Zhang, Bei B
- Nargund, Ravi P
- Hagmann, William K
Producer: 20140619
In:
ACS medicinal chemistry letters vol. 5
Availability: No items available.
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16.
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Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl-1H-benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors. [electronic resource] by
- Cernak, Tim
- Gesmundo, Nathan J
- Dykstra, Kevin
- Yu, Yang
- Wu, Zhicai
- Shi, Zhi-Cai
- Vachal, Petr
- Sperbeck, Donald
- He, Shuwen
- Murphy, Beth Ann
- Sonatore, Lisa
- Williams, Steven
- Madeira, Maria
- Verras, Andreas
- Reiter, Maud
- Lee, Claire Heechoon
- Cuff, James
- Sherer, Edward C
- Kuethe, Jeffrey
- Goble, Stephen
- Perrotto, Nicholas
- Pinto, Shirly
- Shen, Dong-Ming
- Nargund, Ravi
- Balkovec, James
- DeVita, Robert J
- Dreher, Spencer D
Producer: 20170711
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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17.
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Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics. [electronic resource] by
- Wolkenberg, Scott E
- Nolt, M Brad
- Bilodeau, Mark T
- Trotter, B Wesley
- Manley, Peter J
- Kett, Nathan R
- Nanda, Kausik K
- Wu, Zhicai
- Cato, Matthew J
- Kane, Stefanie A
- Kiss, Laszlo
- Spencer, Robert H
- Wang, Jixin
- Lynch, Joseph J
- Regan, Christopher P
- Stump, Gary L
- Li, Bing
- White, Rebecca
- Yeh, Suzie
- Dinsmore, Christopher J
- Lindsley, Craig W
- Hartman, George D
Producer: 20170818
In:
Bioorganic & medicinal chemistry letters vol. 27
Availability: No items available.
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18.
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Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores. [electronic resource] by
- Dong, Shuzhi
- VanGelder, Kelsey
- Shi, Zhi-Cai
- Yu, Yang
- Wu, Zhicai
- Ferguson, Ron
- Guo, Zack Zhiqiang
- Tang, Haifeng
- Frie, Jessica
- Fu, Qinghong
- Gu, Xin
- Priest, Birgit T
- Thomas-Fowlkes, Brande
- Weinglass, Adam
- Margulis, Michael
- Liu, Jessica
- Pai, Lee-Yuh
- Hampton, Caryn
- Haimbach, Robin E
- Owens, Karen
- Tong, Vincent
- Xu, Shiyao
- Hu, Mengwei
- Zingaro, Gloria J
- Morissette, Pierre
- Ehrhart, Juliann
- Roy, Sophie
- Sullivan, Kathleen
- Pasternak, Alexander
Producer: 20170821
In:
Bioorganic & medicinal chemistry letters vol. 27
Availability: No items available.
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19.
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Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC). [electronic resource] by
- Yu, Yang
- Wu, Zhicai
- Shi, Zhi-Cai
- He, Shuwen
- Lai, Zhong
- Cernak, Timothy A
- Vachal, Petr
- Liu, Min
- Liu, Jian
- Hong, Qingmei
- Jian, Tianying
- Guiadeen, Deodial
- Krikorian, Arto
- Sperbeck, Donald M
- Verras, Andreas
- Sonatore, Lisa M
- Murphy, Beth A
- Wiltsie, Judyann
- Chung, Christine C
- Gorski, Judith N
- Liu, Jinqi
- Xiao, Jianying
- Wolff, Michael
- Tong, Sharon X
- Madeira, Maria
- Karanam, Bindhu V
- Shen, Dong-Ming
- Balkovec, James M
- De Vita, Robert J
- Pinto, Shirly
- Nargund, Ravi P
Producer: 20200911
In:
Bioorganic & medicinal chemistry letters vol. 29
Availability: No items available.
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20.
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Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety. [electronic resource] by
- He, Shuwen
- Lai, Zhong
- Hong, Qingmei
- Shang, Jackie
- Reibarkh, Mikhail
- Kuethe, Jeffrey T
- Liu, Jian
- Guiadeen, Deodial
- Krikorian, Arto D
- Cernak, Timothy A
- Dykstra, Kevin D
- Sperbeck, Donald M
- Wu, Zhicai
- Yu, Yang
- Yang, Ginger X
- Jian, Tianying
- Verras, Andreas
- Sonatore, Lisa M
- Wiltsie, Judyann
- Chung, Christine C
- Murphy, Beth A
- Gorski, Judith N
- Liu, Jinqi
- Xiao, Jianying
- Wolff, Michael
- Tong, Sharon X
- Madeira, Maria
- Karanam, Bindhu V
- Shen, Dong-Ming
- Balkovec, James M
- Pinto, Shirly
- Nargund, Ravi P
- DeVita, Robert J
Producer: 20200225
In:
Bioorganic & medicinal chemistry letters vol. 29
Availability: No items available.
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