Results
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1.
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Synthesis and SAR of novel histamine H3 receptor antagonists. [electronic resource] by
- Jesudason, Cynthia D
- Beavers, Lisa S
- Cramer, Jeffrey W
- Dill, Joelle
- Finley, Don R
- Lindsley, Craig W
- Stevens, F Craig
- Gadski, Robert A
- Oldham, Samuel W
- Pickard, R Todd
- Siedem, Christopher S
- Sindelar, Dana K
- Singh, Ajay
- Watson, Brian M
- Hipskind, Philip A
Producer: 20060802
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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2.
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Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones. [electronic resource] by
- Hutchings, Kim M
- Tran, Tuan P
- Ellsworth, Edmund L
- Watson, Brian M
- Sanchez, Joseph P
- Showalter, H D
- Stier, Michael A
- Shapiro, Martin
- Themis Joannides, E
- Huband, Michael
- Nguyen, Dai Q
- Maiti, Samarendra
- Li, Tingsheng
- Tailor, Jyoti
- Thomas, George
- Ha, Chan
- Singh, Rajeshwar
Producer: 20081014
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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3.
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D-phenylglycinol-derived non-covalent factor Xa inhibitors: effect of non-peptidic S4 linkage elements on affinity and anticoagulant activity. [electronic resource] by
- Klimkowski, Valentine J
- Watson, Brian M
- Wiley, Michael R
- Liebeschuetz, John
- Franciskovich, Jeffry B
- Marimuthu, Jothirajah
- Bastian, Jolie A
- Sall, Daniel J
- Smallwood, Jeffrey K
- Chirgadze, Nikolay Y
- Smith, Gerald F
- Foster, Ronald S
- Craft, Trelia
- Sipes, Philip
- Chastain, Marcia
- Sheehan, Scott M
Producer: 20080205
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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4.
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Structure-activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors. [electronic resource] by
- Tran, Tuan P
- Ellsworth, Edmund L
- Sanchez, Joseph P
- Watson, Brian M
- Stier, Michael A
- Showalter, H D Hollis
- Domagala, John M
- Shapiro, Martin A
- Joannides, E Themis
- Gracheck, Stephen J
- Nguyen, Dai Q
- Bird, Paul
- Yip, Judy
- Sharadendu, Anurag
- Ha, Chan
- Ramezani, Saeed
- Wu, Xiujuan
- Singh, Rajeshwar
Producer: 20070515
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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5.
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3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms. [electronic resource] by
- Ellsworth, Edmund L
- Tran, Tuan P
- Showalter, H D Hollis
- Sanchez, Joseph P
- Watson, Brian M
- Stier, Michael A
- Domagala, John M
- Gracheck, Stephen J
- Joannides, E Themis
- Shapiro, Martin A
- Dunham, Steve A
- Hanna, Debra L
- Huband, Michael D
- Gage, Jeffrey W
- Bronstein, Joel C
- Liu, Jia Yeu
- Nguyen, Dai Q
- Singh, Rajeshwar
Producer: 20061205
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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6.
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Preparation and biological evaluation of conformationally constrained BACE1 inhibitors. [electronic resource] by
- Winneroski, Leonard L
- Schiffler, Matthew A
- Erickson, Jon A
- May, Patrick C
- Monk, Scott A
- Timm, David E
- Audia, James E
- Beck, James P
- Boggs, Leonard N
- Borders, Anthony R
- Boyer, Robert D
- Brier, Richard A
- Hudziak, Kevin J
- Klimkowski, Valentine J
- Garcia Losada, Pablo
- Mathes, Brian M
- Stout, Stephanie L
- Watson, Brian M
- Mergott, Dustin J
Producer: 20160226
In:
Bioorganic & medicinal chemistry vol. 23
Availability: No items available.
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7.
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Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site. [electronic resource] by
- Sheehan, Scott M
- Mest, Hans-Juergen
- Watson, Brian M
- Klimkowski, Valentine J
- Timm, David E
- Cauvin, Annick
- Parsons, Stephen H
- Shi, Qing
- Canada, Emily J
- Wiley, Michael R
- Ruehter, Gerd
- Evers, Britta
- Petersen, Soenke
- Blaszczak, Larry C
- Pulley, Shon R
- Margolis, Brandon J
- Wishart, Graham N
- Renson, Beatrice
- Hankotius, Dirk
- Mohr, Michael
- Zechel, Johann-Christian
- Michael Kalbfleisch, J
- Dingess-Hammond, Elizabeth A
- Boelke, Andre
- Weichert, Andreas G
Producer: 20070529
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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8.
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Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor. [electronic resource] by
- May, Patrick C
- Dean, Robert A
- Lowe, Stephen L
- Martenyi, Ferenc
- Sheehan, Scott M
- Boggs, Leonard N
- Monk, Scott A
- Mathes, Brian M
- Mergott, Dustin J
- Watson, Brian M
- Stout, Stephanie L
- Timm, David E
- Smith Labell, Elizabeth
- Gonzales, Celedon R
- Nakano, Masako
- Jhee, Stanford S
- Yen, Mark
- Ereshefsky, Larry
- Lindstrom, Terry D
- Calligaro, David O
- Cocke, Patrick J
- Greg Hall, D
- Friedrich, Stuart
- Citron, Martin
- Audia, James E
Producer: 20120112
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 31
Availability: No items available.
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9.
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Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints. [electronic resource] by
- Winneroski, Leonard L
- Erickson, Jon A
- Green, Steven J
- Lopez, Jose E
- Stout, Stephanie L
- Porter, Warren J
- Timm, David E
- Audia, James E
- Barberis, Mario
- Beck, James P
- Boggs, Leonard N
- Borders, Anthony R
- Boyer, Robert D
- Brier, Richard A
- Hembre, Erik J
- Hendle, Jörg
- Garcia-Losada, Pablo
- Minguez, Jose Miguel
- Mathes, Brian M
- May, Patrick C
- Monk, Scott A
- Rankovic, Zoran
- Shi, Yuan
- Watson, Brian M
- Yang, Zhixiang
- Mergott, Dustin J
Producer: 20210127
In:
Bioorganic & medicinal chemistry vol. 28
Availability: No items available.
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10.
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The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans. [electronic resource] by
- May, Patrick C
- Willis, Brian A
- Lowe, Stephen L
- Dean, Robert A
- Monk, Scott A
- Cocke, Patrick J
- Audia, James E
- Boggs, Leonard N
- Borders, Anthony R
- Brier, Richard A
- Calligaro, David O
- Day, Theresa A
- Ereshefsky, Larry
- Erickson, Jon A
- Gevorkyan, Hykop
- Gonzales, Celedon R
- James, Douglas E
- Jhee, Stanford S
- Komjathy, Steven F
- Li, Linglin
- Lindstrom, Terry D
- Mathes, Brian M
- Martényi, Ferenc
- Sheehan, Scott M
- Stout, Stephanie L
- Timm, David E
- Vaught, Grant M
- Watson, Brian M
- Winneroski, Leonard L
- Yang, Zhixiang
- Mergott, Dustin J
Producer: 20150324
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 35
Availability: No items available.
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11.
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Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1 [electronic resource] by
- Hao, Junliang
- Beck, James P
- Schaus, John M
- Krushinski, Joseph H
- Chen, Qi
- Beadle, Christopher D
- Vidal, Paloma
- Reinhard, Matthew R
- Dressman, Bruce A
- Massey, Steven M
- Boulet, Serge L
- Cohen, Michael P
- Watson, Brian M
- Tupper, David
- Gardinier, Kevin M
- Myers, Jason
- Johansson, Anette M
- Richardson, Jeffery
- Richards, Daniel S
- Hembre, Erik J
- Remick, David M
- Coates, David A
- Bhardwaj, Rajni M
- Diseroad, Benjamin A
- Bender, David
- Stephenson, Greg
- Wolfangel, Craig D
- Diaz, Nuria
- Getman, Brian G
- Wang, Xu-Shan
- Heinz, Beverly A
- Cramer, Jeff W
- Zhou, Xin
- Maren, Deanna L
- Falcone, Julie F
- Wright, Rebecca A
- Mitchell, Stephen N
- Carter, Guy
- Yang, Charles R
- Bruns, Robert F
- Svensson, Kjell A
Producer: 20200615
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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