Preparation and biological evaluation of conformationally constrained BACE1 inhibitors. [electronic resource]
Producer: 20160226Description: 3260-8 p. digitalISSN:- 1464-3391
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Animals
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Brain Chemistry
- Bridged Bicyclo Compounds -- chemical synthesis
- Crystallography, X-Ray
- Drug Design
- Humans
- Mice
- Molecular Conformation
- Molecular Docking Simulation
- Protease Inhibitors -- chemical synthesis
- Stereoisomerism
- Thiazines -- chemical synthesis
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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