Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. [electronic resource]
Producer: 20200225ISSN:- 2050-084X
- ATP-Binding Cassette Transporters -- metabolism
- Activating Transcription Factor 6 -- antagonists & inhibitors
- CRISPR-Cas Systems -- genetics
- Endoplasmic Reticulum -- drug effects
- HEK293 Cells
- Hep G2 Cells
- Humans
- Organelles -- drug effects
- Peroxisomes -- drug effects
- Phenotype
- Protein Binding -- drug effects
- Small Molecule Libraries -- pharmacology
- Unfolded Protein Response -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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