Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its D,L-polylactide microparticle formulation. [electronic resource]
Producer: 20151002Description: 56-65 p. digitalISSN:- 1873-4596
- Animals
- Antioxidants -- metabolism
- Apoptosis -- drug effects
- Azoles -- pharmacology
- Biomimetics
- Cell Proliferation -- drug effects
- Cells, Cultured
- Chemistry, Pharmaceutical
- Drug Compounding
- Glutathione -- metabolism
- Glutathione Peroxidase -- chemistry
- Glutathione S-Transferase pi -- antagonists & inhibitors
- Humans
- Hydrogen Peroxide -- metabolism
- Isoindoles
- K562 Cells
- Kinetics
- MCF-7 Cells
- Mice
- Mice, Knockout
- Organoselenium Compounds -- pharmacology
- Oxidative Stress -- drug effects
- Polyesters -- chemistry
- Reactive Oxygen Species -- metabolism
- Selenium Compounds -- pharmacology
- Sulfhydryl Compounds -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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