Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15. [electronic resource]
Producer: 20021119Description: 63-80 p. digitalISSN:- 1044-7431
- A Kinase Anchor Proteins
- Adaptor Proteins, Signal Transducing
- Animals
- Carrier Proteins -- metabolism
- Catalytic Domain -- physiology
- Cell Membrane -- enzymology
- Cells, Cultured
- Cyclic AMP-Dependent Protein Kinase Type II
- Cyclic AMP-Dependent Protein Kinases -- antagonists & inhibitors
- Enzyme Inhibitors -- pharmacology
- Hippocampus -- enzymology
- Humans
- In Vitro Techniques
- Membrane Potentials -- physiology
- Membrane Proteins -- metabolism
- NAV1.2 Voltage-Gated Sodium Channel
- Nerve Tissue Proteins -- drug effects
- Neuronal Plasticity -- physiology
- Neurons -- enzymology
- Phosphorylation
- Protein Kinase C -- antagonists & inhibitors
- Protein Structure, Tertiary -- physiology
- Saccharomyces cerevisiae
- Serine -- metabolism
- Sodium -- metabolism
- Sodium Channels -- drug effects
- Synaptic Transmission -- physiology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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