Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15.

Cantrell, Angela R

Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15. [electronic resource] - Molecular and cellular neurosciences Sep 2002 - 63-80 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1044-7431

10.1006/mcne.2002.1162 doi


A Kinase Anchor Proteins
Adaptor Proteins, Signal Transducing
Animals
Carrier Proteins--metabolism
Catalytic Domain--physiology
Cell Membrane--enzymology
Cells, Cultured
Cyclic AMP-Dependent Protein Kinase Type II
Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors
Enzyme Inhibitors--pharmacology
Hippocampus--enzymology
Humans
In Vitro Techniques
Membrane Potentials--physiology
Membrane Proteins--metabolism
NAV1.2 Voltage-Gated Sodium Channel
Nerve Tissue Proteins--drug effects
Neuronal Plasticity--physiology
Neurons--enzymology
Phosphorylation
Protein Kinase C--antagonists & inhibitors
Protein Structure, Tertiary--physiology
Saccharomyces cerevisiae
Serine--metabolism
Sodium--metabolism
Sodium Channels--drug effects
Synaptic Transmission--physiology