Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity. [electronic resource]
Producer: 20050309Description: 244-57 p. digitalISSN:- 0041-008X
- 9,10-Dimethyl-1,2-benzanthracene -- pharmacokinetics
- Animals
- Aryl Hydrocarbon Hydroxylases -- biosynthesis
- Benzo(a)pyrene -- pharmacokinetics
- Bone Marrow Cells -- drug effects
- Carcinogens, Environmental -- pharmacokinetics
- Cells, Cultured
- Cytochrome P-450 CYP1A1 -- biosynthesis
- Cytochrome P-450 CYP1B1
- DNA Adducts -- biosynthesis
- Enzyme Induction
- In Situ Hybridization
- Liver -- drug effects
- Lung -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Polycyclic Compounds -- pharmacokinetics
- RNA, Messenger -- biosynthesis
- Receptors, Aryl Hydrocarbon -- physiology
- Tissue Distribution
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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