Defective repair of oxidative dna damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase. [electronic resource]
Producer: 20090619Description: 3589-96 p. digitalISSN:- 1538-7445
- Animals
- BRCA1 Protein
- Breast Neoplasms -- enzymology
- Cell Line, Tumor
- DNA Damage
- DNA Glycosylases -- antagonists & inhibitors
- DNA Repair
- Genes, BRCA1
- Humans
- Mammary Neoplasms, Experimental -- enzymology
- Mice
- Oxidation-Reduction
- Poly(ADP-ribose) Polymerase Inhibitors
- Poly(ADP-ribose) Polymerases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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