Defective repair of oxidative dna damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase.

Alli, Elizabeth

Defective repair of oxidative dna damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase. [electronic resource] - Cancer research Apr 2009 - 3589-96 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1538-7445

10.1158/0008-5472.CAN-08-4016 doi


Animals
BRCA1 Protein
Breast Neoplasms--enzymology
Cell Line, Tumor
DNA Damage
DNA Glycosylases--antagonists & inhibitors
DNA Repair
Genes, BRCA1
Humans
Mammary Neoplasms, Experimental--enzymology
Mice
Oxidation-Reduction
Poly(ADP-ribose) Polymerase Inhibitors
Poly(ADP-ribose) Polymerases--metabolism