Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening. [electronic resource]
Producer: 20201023Description: 286-292 p. digitalISSN:- 1745-7254
- Antineoplastic Agents -- administration & dosage
- Binding Sites
- CREB-Binding Protein -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Discovery -- methods
- Fluorescence Resonance Energy Transfer
- High-Throughput Screening Assays
- Humans
- Inhibitory Concentration 50
- Leukemia -- drug therapy
- Models, Molecular
- Protein Domains
- Small Molecule Libraries
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Publication Type: Journal Article
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