Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome. [electronic resource]
Producer: 20200925Description: 6543-6553 p. digitalISSN:- 1582-4934
- Amiloride -- pharmacology
- Animals
- Cathepsin B -- antagonists & inhibitors
- Epithelial Sodium Channel Blockers -- pharmacology
- Epithelial Sodium Channels -- metabolism
- Glomerulosclerosis, Focal Segmental -- enzymology
- Hypertension -- etiology
- Intracellular Signaling Peptides and Proteins -- genetics
- Kidney Tubules -- cytology
- Lysosomes -- enzymology
- Membrane Proteins -- genetics
- Mice
- Mice, Transgenic
- Nephrotic Syndrome -- complications
- Proteinuria -- metabolism
- Proteolysis
- Sodium -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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