Results
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Stromelysin-3 over-expression enhances tumourigenesis in MCF-7 and MDA-MB-231 breast cancer cell lines: involvement of the IGF-1 signalling pathway. [electronic resource] by
- Kasper, Grit
- Reule, Matthias
- Tschirschmann, Miriam
- Dankert, Niels
- Stout-Weider, Karen
- Lauster, Roland
- Schrock, Evelin
- Mennerich, Detlev
- Duda, Georg N
- Lehmann, Kerstin E
Producer: 20070306
In:
BMC cancer vol. 7
Availability: No items available.
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3.
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The heat shock protein 90 inhibitor, AT13387, displays a long duration of action in vitro and in vivo in non-small cell lung cancer. [electronic resource] by
- Graham, Brent
- Curry, Jayne
- Smyth, Tomoko
- Fazal, Lynsey
- Feltell, Ruth
- Harada, Isobel
- Coyle, Joe
- Williams, Brian
- Reule, Matthias
- Angove, Hayley
- Cross, David M
- Lyons, John
- Wallis, Nicola G
- Thompson, Neil T
Producer: 20120416
In:
Cancer science vol. 103
Availability: No items available.
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4.
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Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL-positive leukemic cells. [electronic resource] by
- Tanaka, Ruriko
- Squires, Matthew S
- Kimura, Shinya
- Yokota, Asumi
- Nagao, Rina
- Yamauchi, Takahiro
- Takeuchi, Miki
- Yao, Hisayuki
- Reule, Matthias
- Smyth, Tomoko
- Lyons, John F
- Thompson, Neil T
- Ashihara, Eishi
- Ottmann, Oliver G
- Maekawa, Taira
Producer: 20101027
In:
Blood vol. 116
Availability: No items available.
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5.
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AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase that induces pharmacodynamic changes and inhibits human tumor xenograft growth. [electronic resource] by
- Grimshaw, Kyla M
- Hunter, Lisa-Jane K
- Yap, Timothy A
- Heaton, Simon P
- Walton, Mike I
- Woodhead, Steven J
- Fazal, Lynsey
- Reule, Matthias
- Davies, Thomas G
- Seavers, Lisa C
- Lock, Victoria
- Lyons, John F
- Thompson, Neil T
- Workman, Paul
- Garrett, Michelle D
Producer: 20100820
In:
Molecular cancer therapeutics vol. 9
Availability: No items available.
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6.
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Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. [electronic resource] by
- Howard, Steven
- Berdini, Valerio
- Boulstridge, John A
- Carr, Maria G
- Cross, David M
- Curry, Jayne
- Devine, Lindsay A
- Early, Theresa R
- Fazal, Lynsey
- Gill, Adrian L
- Heathcote, Michelle
- Maman, Sarita
- Matthews, Julia E
- McMenamin, Rachel L
- Navarro, Eva F
- O'Brien, Michael A
- O'Reilly, Marc
- Rees, David C
- Reule, Matthias
- Tisi, Dominic
- Williams, Glyn
- Vinković, Mladen
- Wyatt, Paul G
Producer: 20090223
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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7.
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Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design. [electronic resource] by
- Wyatt, Paul G
- Woodhead, Andrew J
- Berdini, Valerio
- Boulstridge, John A
- Carr, Maria G
- Cross, David M
- Davis, Deborah J
- Devine, Lindsay A
- Early, Theresa R
- Feltell, Ruth E
- Lewis, E Jonathan
- McMenamin, Rachel L
- Navarro, Eva F
- O'Brien, Michael A
- O'Reilly, Marc
- Reule, Matthias
- Saxty, Gordon
- Seavers, Lisa C A
- Smith, Donna-Michelle
- Squires, Matt S
- Trewartha, Gary
- Walker, Margaret T
- Woolford, Alison J-A
Producer: 20080910
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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AT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity. [electronic resource] by
- Yap, Timothy A
- Walton, Mike I
- Grimshaw, Kyla M
- Te Poele, Robert H
- Eve, Paul D
- Valenti, Melanie R
- de Haven Brandon, Alexis K
- Martins, Vanessa
- Zetterlund, Anna
- Heaton, Simon P
- Heinzmann, Kathrin
- Jones, Paul S
- Feltell, Ruth E
- Reule, Matthias
- Woodhead, Steven J
- Davies, Thomas G
- Lyons, John F
- Raynaud, Florence I
- Eccles, Suzanne A
- Workman, Paul
- Thompson, Neil T
- Garrett, Michelle D
Producer: 20130403
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 18
Availability: No items available.
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