Defining the potential of aglycone modifications for affinity/selectivity enhancement against medically relevant lectins: synthesis, activity screening, and HSQC-based NMR analysis. [electronic resource]
Producer: 20150824Description: 126-39 p. digitalISSN:- 1439-7633
- Acetylglucosamine -- chemistry
- Alkynes -- chemistry
- Amino Sugars -- chemical synthesis
- Azides -- chemistry
- Blood Proteins
- Carbohydrate Sequence
- Catalysis
- Cycloaddition Reaction
- Galectin 1 -- antagonists & inhibitors
- Galectin 3 -- antagonists & inhibitors
- Galectins -- antagonists & inhibitors
- Glycosides -- chemical synthesis
- Humans
- Hydrophobic and Hydrophilic Interactions
- Ligands
- Models, Molecular
- Molecular Sequence Data
- Nitrophenylgalactosides -- chemistry
- Protein Binding
- Structure-Activity Relationship
- Triazoles -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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