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Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands. [electronic resource] by
- Ghosh, Arun K
- Jadhav, Ravindra D
- Simpson, Hannah
- Kovela, Satish
- Osswald, Heather
- Agniswamy, Johnson
- Wang, Yuan-Fang
- Hattori, Shin-Ichiro
- Weber, Irene T
- Mitsuya, Hiroaki
Producer: 20181211
In:
European journal of medicinal chemistry vol. 160
Availability: No items available.
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Highly potent HIV-1 protease inhibitors with novel tricyclic P2 ligands: design, synthesis, and protein-ligand X-ray studies. [electronic resource] by
- Ghosh, Arun K
- Parham, Garth L
- Martyr, Cuthbert D
- Nyalapatla, Prasanth R
- Osswald, Heather L
- Agniswamy, Johnson
- Wang, Yuan-Fang
- Amano, Masayuki
- Weber, Irene T
- Mitsuya, Hiroaki
Producer: 20131111
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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14.
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Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis. [electronic resource] by
- Ghosh, Arun K
- R Nyalapatla, Prasanth
- Kovela, Satish
- Rao, Kalapala Venkateswara
- Brindisi, Margherita
- Osswald, Heather L
- Amano, Masayuki
- Aoki, Manabu
- Agniswamy, Johnson
- Wang, Yuan-Fang
- Weber, Irene T
- Mitsuya, Hiroaki
Producer: 20190603
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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15.
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Design of HIV-1 Protease Inhibitors with Amino-bis-tetrahydrofuran Derivatives as P2-Ligands to Enhance Backbone-Binding Interactions: Synthesis, Biological Evaluation, and Protein-Ligand X-ray Studies. [electronic resource] by
- Ghosh, Arun K
- Martyr, Cuthbert D
- Osswald, Heather L
- Sheri, Venkat Reddy
- Kassekert, Luke A
- Chen, Shujing
- Agniswamy, Johnson
- Wang, Yuan-Fang
- Hayashi, Hironori
- Aoki, Manabu
- Weber, Irene T
- Mitsuya, Hiroaki
Producer: 20151214
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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16.
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Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants. [electronic resource] by
- Ghosh, Arun K
- Rao, Kalapala Venkateswara
- Nyalapatla, Prasanth R
- Osswald, Heather L
- Martyr, Cuthbert D
- Aoki, Manabu
- Hayashi, Hironori
- Agniswamy, Johnson
- Wang, Yuan-Fang
- Bulut, Haydar
- Das, Debananda
- Weber, Irene T
- Mitsuya, Hiroaki
Producer: 20170619
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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17.
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Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants. [electronic resource] by
- Ghosh, Arun K
- Rao, Kalapala Venkateswara
- Nyalapatla, Prasanth R
- Kovela, Satish
- Brindisi, Margherita
- Osswald, Heather L
- Sekhara Reddy, Bhavanam
- Agniswamy, Johnson
- Wang, Yuan-Fang
- Aoki, Manabu
- Hattori, Shin-Ichiro
- Weber, Irene T
- Mitsuya, Hiroaki
Producer: 20190321
In:
ChemMedChem vol. 13
Availability: No items available.
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18.
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Modular, stereocontrolled C [electronic resource] by
- Shang, Ming
- Feu, Karla S
- Vantourout, Julien C
- Barton, Lisa M
- Osswald, Heather L
- Kato, Nobutaka
- Gagaring, Kerstin
- McNamara, Case W
- Chen, Gang
- Hu, Liang
- Ni, Shengyang
- Fernández-Canelas, Paula
- Chen, Miao
- Merchant, Rohan R
- Qin, Tian
- Schreiber, Stuart L
- Melillo, Bruno
- Yu, Jin-Quan
- Baran, Phil S
Producer: 20200313
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 116
Availability: No items available.
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19.
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A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant. [electronic resource] by
- Agnihothram, Sudhakar
- Yount, Boyd L
- Donaldson, Eric F
- Huynh, Jeremy
- Menachery, Vineet D
- Gralinski, Lisa E
- Graham, Rachel L
- Becker, Michelle M
- Tomar, Sakshi
- Scobey, Trevor D
- Osswald, Heather L
- Whitmore, Alan
- Gopal, Robin
- Ghosh, Arun K
- Mesecar, Andrew
- Zambon, Maria
- Heise, Mark
- Denison, Mark R
- Baric, Ralph S
Producer: 20141027
In:
mBio vol. 5
Availability: No items available.
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20.
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A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency. [electronic resource] by
- Aoki, Manabu
- Hayashi, Hironori
- Rao, Kalapala Venkateswara
- Das, Debananda
- Higashi-Kuwata, Nobuyo
- Bulut, Haydar
- Aoki-Ogata, Hiromi
- Takamatsu, Yuki
- Yedidi, Ravikiran S
- Davis, David A
- Hattori, Shin-Ichiro
- Nishida, Noriko
- Hasegawa, Kazuya
- Takamune, Nobutoki
- Nyalapatla, Prasanth R
- Osswald, Heather L
- Jono, Hirofumi
- Saito, Hideyuki
- Yarchoan, Robert
- Misumi, Shogo
- Ghosh, Arun K
- Mitsuya, Hiroaki
Producer: 20180619
In:
eLife vol. 6
Availability: No items available.
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