Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants. [electronic resource]
Producer: 20170619Description: 4267-4278 p. digitalISSN:- 1520-4804
- Benzothiazoles -- chemistry
- Crystallography, X-Ray
- Drug Design
- Drug Resistance, Multiple, Viral
- Furans -- chemistry
- HIV Infections -- drug therapy
- HIV Protease -- chemistry
- HIV Protease Inhibitors -- chemistry
- HIV-1 -- chemistry
- Humans
- Ligands
- Molecular Docking Simulation
- Pyrans -- chemistry
- Structure-Activity Relationship
- Sulfonamides -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
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