Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells. [electronic resource]
Producer: 20210614Description: 1515-1528 p. digitalISSN:- 1860-7187
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- chemical synthesis
- Glutathione Peroxidase -- antagonists & inhibitors
- Heterocyclic Compounds -- chemical synthesis
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Molecular Structure
- Oxidative Stress -- drug effects
- Structure-Activity Relationship
- Sulfides -- chemical synthesis
- Tumor Cells, Cultured
- Glutathione Peroxidase GPX1
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Publication Type: Journal Article
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