Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. [electronic resource]
Producer: 20110720Description: 63-71 p. digitalISSN:- 1432-1041
- Adult
- Analgesics, Opioid -- adverse effects
- Cross-Over Studies
- Cytochrome P-450 CYP2D6 Inhibitors
- Cytochrome P-450 CYP3A
- Cytochrome P-450 CYP3A Inhibitors
- Double-Blind Method
- Drug Interactions
- Genotype
- Humans
- Ketoconazole -- pharmacology
- Miosis
- Morphinans -- metabolism
- Oxycodone -- adverse effects
- Oxymorphone -- metabolism
- Pain Measurement
- Paroxetine -- pharmacology
- Placebos
- Young Adult
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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