Novel engineered TRAIL-based chimeric protein strongly inhibits tumor growth and bypasses TRAIL resistance. [electronic resource]
Producer: 20210405Description: 1117-1130 p. digitalISSN:- 1097-0215
- A549 Cells
- Animals
- Antineoplastic Agents -- metabolism
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Female
- HCT116 Cells
- HT29 Cells
- Hep G2 Cells
- Humans
- Mice, SCID
- Neoplasms -- drug therapy
- Protein Engineering -- methods
- Recombinant Fusion Proteins -- genetics
- TNF-Related Apoptosis-Inducing Ligand -- genetics
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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